ONE YEAR FOLLOW-UP STUDY OF QUALITY OF LIFE AMONG OPIOID SUBSTITUTION THERAPY CLIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 2
Abstract
BACKGROUND Opioid Substitution Therapy (OST) is a process in which opioid-dependent injecting drug users (IDUs) are provided with longacting opioid agonist medications like buprenorphine for a long period of time under medical supervision along with psycho-social interventions. The QOL is impaired among opioid dependent IDUs. The present study was undertaken to determine the quality of life among IDUs on opioid substitution therapy. The aim of this study is to see changes in Quality of Life of Opioid-Dependent IDUs attending OST Centre of a Tertiary Government Hospital over a year. MATERIALS AND METHODS A prospective observational study was conducted on 100 patients attending the OST centre of a tertiary government hospital, who were being administered buprenorphine. Identification data was obtained at baseline and QOL scores obtained using WHOQOLBREF at baseline and at four follow-ups, i.e. after 3 months, 6 months, 9 months and 1 year. After excluding the dropouts, 68 subjects were taken into account to assess QOL. A repeated measuring design (Analysis of Variance) was applied to assess changes in the quality of life at baseline and at follow-ups. RESULTS Scores of WHOQOL-BREF when compared from baseline to end of the study showed statistically significant (p < 0.01) improvement in all the four domains of WHOQOL-BREF, i.e. physical, psychological, social and environment. CONCLUSION The present study indicates that buprenorphine is a useful long-term maintenance treatment for opioid dependent IDUs. So OST programmes should be expanded further for curbing injecting drug use and improving quality of life.
Authors and Affiliations
Sukrant Vir, Rajiv Arora, Parshottam Dass Garg
Keywords
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- EP ID EP284514
- DOI 10.14260/jemds/2018/29
- Views 48
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