Organic causes of abnormal uterine bleeding-A clinico- pathological study based on PALM category of FIGO classification
Journal Title: Indian Journal of Pathology and Oncology - Year 2017, Vol 4, Issue 2
Abstract
Background: Abnormal uterine bleeding (AUB) is one of the most common debilitating menstrual problems and has remained one of the most frequent indications for hysterectomy in developing countries. The problem is common worldwide but causes may vary from one region to another. In about 25% of the patients, the abnormal uterine bleeding is the result of a well-defined organic abnormality. Materials and Method: It was a five year study conducted at a tertiary care hospital, Mumbai. Total of 804 Women who underwent surgical resections and biopsies with complaints of AUB were included in the study and histopathological spectrum of structural pathology was determined. Results: Most common age group affected was 36-45 years. Uterine corpus was common site of pathology (80.2%), followed by cervix (17.4%) Isolated pathology was found in 88.9% cases while multiple pathology in 10.1% cases. Benign pathology formed largest group (82.34%), commonest being leiomyoma (71.6%). Malignancy seen in 14.8% cases, most common malignancy being squamous cell carcinoma (72.72%). Menorrhagia was commonest presentation (64.6%), followed by postmenopausal bleeding (20%) & polymenorrhagia (14.6%). In postmenopausal age group, malignancy was (46.3%) more as compared to age <40 years (8.7%). Rare cases presenting as AUB were encountered viz. serous cystadenoma, mature cystic teratoma and serous cystadenocarcinoma of ovary, malignant mixed mullerian tumor of uterus, metastasis to uterine corpus, and small round cell tumor of cervix. Conclusion: Frequency of benign endometrial pathology as underlying organic cause of AUB is quite high. However, histopathological spectrum in patients with AUB is quite variable with respect to age with increased chances of detecting malignancy in elder females. Therefore Histopathological examination of endometrium should be done generously in women presenting with abnormal uterine bleeding especially after the age of 40 years to rule out malignancy.
Authors and Affiliations
Madhu Chaturvedi, Sangita Margam, Shweta Azad
Keywords
Related Articles
- EP ID EP312821
- DOI 10.18231/2394-6792.2017.0051
- Views 47
- Downloads 0
Giant axillary schwannoma: diagnosed on FNAC
Schwannomas are benign neoplasms of the nerve sheaths. They are commonly known to occur in the head and neck region. Brachial plexus schwannomas are extremely rare. Diagnosis using fine needle aspiration plays a vital ro...
Organic causes of abnormal uterine bleeding-A clinico- pathological study based on PALM category of FIGO classification
Background: Abnormal uterine bleeding (AUB) is one of the most common debilitating menstrual problems and has remained one of the most frequent indications for hysterectomy in developing countries. The problem is common...
Rhinosporidiosis- A retrospection
Rhinosporidiosis is a chronic granulomatous disease caused by Rhinosporidium seeberi It is endemic in the coastal region of India where agriculture is the most common occupation It grows in stagnant water and transepithe...
Comparative evaluation of thin smear, thick smear and antigen detection test in the diagnosis of malaria
Introduction: Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. There are many Techniques available for Detection of malarial pa...
Utility of fine needle aspiration cytology (FNAC) in the diagnosis of soft tissue tumors and tumor like lesions
Introduction Fine needle aspiration cytology FNAC forms one of the first diagnostic tools in evaluation of soft tissue lesions Aim of this study was to evaluate the role of FNAC in the primary diagnosis of soft tissue tu...