Pattern of surgical chemoprophylaxis in cesarean section and hysterectomy patients: an observational prospective study at tertiary care teaching hospital
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2019, Vol 8, Issue 2
Abstract
Background Cesarean section and hysterectomy are the clean contaminated type of surgeries. Most of the developed countries have developed guidelines for appropriate and rational use of prophylactic antibiotics to reduce post-operative infectious complications. Objective To analyze patterns of antibiotic use as surgical prophylaxis in patients operated for cesarean section and hysterectomy. Method Longitudinal observational study was carried out in patients undergoing cesarean section and hysterectomy at a tertiary care teaching hospital between December 2012 and November 2013.A specially designed proforma was used to collect the data of pre-operative patients. The data was analyzed by SPSS software. Results Out of 270 patients enrolled in the study, 209 patients were operated for cesarean section, with most common presenting age group 19-24 years while 61 patients were operated for hysterectomy with common age group of 41-45 years. The most frequently used prophylaxis was injection cefotaxime in more than 80% of cases. Out of 270 patients, 10 developed surgical site infection (SSI). Six patients developed SSI in patients operated for cesarean section while four cases of SSI were found among patients operated for abdominal hysterectomy. Conclusion Single dose of injection cefotaxime was most frequently used surgical prophylaxis in cesarean section and hysterectomy patients pre-operatively. Prophylactic antibiotics were not prescribed according to standard guidelines.
Authors and Affiliations
Dr Krutika Bhatt
Keywords
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