PHYTOCHEMICAL AND CLINICAL EVALUATION OF SARIBA (HEMIDESMUS INDICUS) ON WOUND HEALING
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 3
Abstract
Present study was carried out to screen the phyto-chemical and clinical evaluation of wound healing property of Sariba (Hemidesmus indicus) root paste on chronic wounds. Physico-chemical analysis of Hemidesmus indicus like loss on drying, total ash, acid insoluble ash, water soluble ash and total alkaloids were determined. HPTLC was also performed. In the clinical study, 30 patients of chronic wounds of either sex were randomly selected. Site of the wound, shape, size, pain, discharge, floor and unhealthy granulation were recorded on day 0 and observed on 15, 30, 45 days or completion of healing. Progress of granulation, scar type, shape, size and clinical symptoms were also assessed. The trail drug showed an increase in the rate of wound contraction and increase in the percentage of epithelialisation. The study authenticated that Hemidesmus indicus possesses significant wound healing activity.
Authors and Affiliations
Vijaya Kurapati , K. Nishteswar
Keywords
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