PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF SELECTED MANGO (MANGIFERA INDICA L.) AND AVOCADO (PERSEA AMERICANA) FRUITS IN ILLU ABABOR ZONE, OROMIA REGIONAL STATE, ETHIOPIA
Journal Title: Indo American Journal of Pharmaceutical Research - Year 2017, Vol 7, Issue
Abstract
Abstract Mango (Mangifera indica L.) and Avocado (Persea americana) fruits are rich in bioactive molecules that protect human cells against the detrimental effect of free radicals. The phytochemical analysis revealed the Presence of alkaloids, terpenoids, saponins, tannins, phenolics and flavonoids in both fruits. The free radical scavenging activity using total antioxidant capacity of the phosphomolybdenum method and hydrogen peroxide method were carried out on the water extracts of mango and avocado fruits. The order of antioxidant potential according to phosphomolybdenum method and hydrogen peroxide method was found to be higher in Mangifera indica L. than in Persea americana. The result for the total antioxidant capacity of the measured concentration (0.1 - 0.3 mg/ml) had mangifera indica showing the higher capacity with 0.372 mg Ascorbic Acid Equivalence (AAE) and Persea americana be with 0.265 mg Ascorbic Acid Equivalence (AAE). Further, the hydrogen peroxide scavanging activity was recorded maximum for Mangifera indica L. (70.67%) and (68%) for Persea americana. Phytochemical screening on the extracts revealed the presence of alkaloids, phenolics, terpenoids, flavonoids, saponins, and tannins. The results revealed that the antioxidant activity of mango fruit extracts is greater than that of avocado. The antioxidant activities of the same fruits type differ from place to place even in the same zone.
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN HYDROCHLORIDE AND FLUOCINOLONE ACETONIDE IN THEIR SYNTHETIC MIXTURE
Abstract The present research work aims to develop a simple, precise, accurate, rapid, reproducible and economical method for the estimation of Fluocinolone acetonide and Ciprofloxacin hydrochloride in their synthetic mi...
A REVIEW ON MEDICINAL PLANTS AND HERBAL DRUG FORMULATIONS USED IN DIABETES MELLITUS
Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. It is caused by the deficiency or ineffectiv...
Review Article: Novel Approach for Colon Targeted Drug Delivery
Colonic drug absorption, as an alternative to parenteral drug delivery, is evaluated for its potential advantages and limitations. Methodologies for studying and enhancing colonic drug absorption are discussed with empha...
EVALUATION OF ANTHELMINTIC ACTION OF EMBLICA OFFICINALIS LEAVES EXTRACT ON INDIAN EARTH WORM
The aim of present study highlights the evaluation of anthelmintic activity of Emblica officinalis leave extract in experimental adult Indian earthworm Pheretima posthuma. The shade dried leaves were extracted with ethyl...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF SOFOSBUVIR AND DACLATASVIR DRUG PRODUCT BY RP-HPLC METHOD
Abstract Analytical method was developed for the estimation of Sofosbuvir and Daclatasvir drug substance by liquid chromatography. The chromatographic separation was achieved on C18 column (XTerra RP18 150*4.6, 5um) at a...