Pregnancy outcome of day 3 versus day 5 embryo transfer: A retrospective analysis
Journal Title: Asian Pacific Journal of Reproduction - Year 2017, Vol 6, Issue 2
Abstract
Objective: To compare the pregnancy rate between day 3 and day 5 transfer regardless grades of embryos and number of transferred embryo. Methods: Retrospective cohort, a total of seven hundred and four patients met our inclusion criteria, with 411 had day 3 embryo transfer and 293 had day 5 embryo transfer. The patients who were older than 40 years old were excluded. Embryo transfer was carried out in all patients in both transfer groups. Results: Both clinical pregnancy rate and implantation rate did not show any statistically significant difference between the day 3 and day five transfer groups. These were 44% vs. 45% with P=0.82 and 19% vs. 19% with P=0.99 respectively. An increase of miscarriage rate with day 5 embryo transferred compare with day 3 (12.0% vs. 4.4%, P=0.01), but no significant difference was found about biochemical pregnancy rate (P=0.52). Conclusions: Transferring embryo at day 5 may not provide any additional benefit over day 3 transfers to patients. In addition, it increases the risk of miscarriage. Further studies of this issue needed for confirming our findings.
Authors and Affiliations
Samaher Alfaraj, Fatima Alzaher, Sahar Alshwaiaer, Anwar Ahmed
Keywords
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- EP ID EP240387
- DOI 10.12980/apjr.6.20170208
- Views 195
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