Prospective randomized controlled study to compare the postoperative analgesic efficacy of intravenous dexmedetomidine and pethidine on patients undergoing lumbosacral spine surgeries
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 4
Abstract
Introduction Spine surgeries especially spine fusion surgeries cause severe postoperative pain hampering convalescence This is a randomized double blind controlled study comparing the analgesic efficacy of postoperative intravenous pethidine and dexmedetomidine in patients undergoing lumbosacral spine surgeriesMaterials and Methods After connecting patients to vital parameters monitor patients were given general anaesthesia induced with fentanyl 2mcgkg propofol 2mgkg in graded doses and rocuronium 06mgkg to facilitate tracheal intubation All patients received 1 gram paracetamol iv slow infusion intraoperatively After one and a half hours of surgery injection fentanyl 1mcgkg was repeated After extubation and shifting the patients to PACU patients were randomly allotted either group Ppethidine group or group Ddexmedetomidine group by computerised randomization Group P patients received injection pethidine 05mgkg loading dose diluted in 5 ml of distilled water slow iv followed by 015mgkghr infusion for 24hrs Group D patients received injection dexmedetomidine 1mcgkg bolus over 15 minutes followed by infusion of 05mcgkgmin Pulse rate blood pressure oxygen saturation respiratory rate VAS score and sedation score were monitored every 5 minutes for first 15 minutes every 15 minutes for 1 hour every hour till 6th hour then 12th hour and 24th hourResults Dexmedetomidine has a faster on set of analgesic effect 10 minutes compared to pethidine 30 minutes provides better analgesia and manageable hemodynamics but causes more sedation with an average sedation score of 283 compared to pethidineConclusion Dexmedetomidine is a better analgesic in the postoperative period compared to pethidine Keywords Dexmedetomidine Lumbosacral spine surgeries Pethidine
Authors and Affiliations
S Sindhuja
Keywords
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- EP ID EP476528
- DOI 10.18231/2394-4994.2018.0112
- Views 71
- Downloads 0
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