Serum Vitamin D Status in reflux nephropathy
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 12
Abstract
This study was designed to assess serum vitamin D status (25-OHD) in the reflux nephropathy patients and to compare it with a no reflux nephropathy control group. It also aimed to investigate the correlation of serum vitamin D level with vesicoureteral reflux severity and invalidation experiences.A total of 230 consecutive patients with RN and 240 Non RN control participants were enrolled. Venous blood samples were drawn from all participants to evaluate serum 25-OHD levels. Mann-Whitney tests and multiple logistic regression analyses were performed and Spearman's correlations were calculated.470 children were examined (230 RN and 240 NRN). The deficiency(<10ng/ml )36 % in RN and 2% NRN( p-value 0.0001), insufficiency(10-30ng/ml)43% in RN and 5% in NRN (p-value=0.0003) , sufficient(30-150ng/ml)21% in RN and 93% in NRN(p-value=0.002) and potential intoxication (>150ng/ml) 0% in two group of vitamin D were observed in analyzed children with RN . There were no significant differences in serum calcium, phosphorus and gender.This study showed that although high rates of vitamin D insufficiency or deficiency were seen among RN patients and NRN participants, Addressing of invalidation experience especially by the patient's spouse is important in management of RN. Keywords:reflux nephropathy, serum vitamin D status.
Authors and Affiliations
Parsa Yousefichaijan, Masoud RezagholiZamnjany, Fatemeh Dorreh, Fakhreddin Shariatmadari, Yazdan Ghandi, Saeed Alinejad, Manijeh Kahbazi, Sara Khalighi
Keywords
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