Study of Clinical and Hematological Profile in Smear Positive Malaria Patients.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 2
Abstract
Introduction Malaria is a major health problem in many parts of India. Several factorshave been attributed to increased morbidity and mortality in malaria with altered hematological parameters playing an important role. Objective The hematological changes usually associated with malaria are well known. This study was conducted to estimate and compare the predominance & severity of hematological changes in common types of malaria and their clinical correlation. Method All patients who presented to Department of Medicine and proved to be malarial parasite positive through peripheral blood smear or antigen detection method were included in the study and underwent detailed clinical history, thorough clinical examination and investigated with hematological parameter. Results Total 200 patients were enrolled in the study. Out of 200 patient 143 (71.5%) had vivax malaria, 48(24%) had falciparum malaria and only 9(4.5%) cases with mixed infection. Anemia was seen in 163 cases (81.5%) of patients and Thrombocytopenia was seen in 175 cases (87.5%), Leucopenia was seen in 51(25.1%) cases. Fevers, chills, sweating were leading clinical presentation in all three forms. Splenomegaly was leading sign in all forms, mainly in falciprum malaria. Anemia and thrombocytopenia were more common in plasmodium falciparum and mixed infections as compared to plasmodium vivax. Conclusion Malaria must be considered as a leading differential diagnosis in acute febrile patients with more abnormalities like splenomegaly, fall in Hemoglobin level, low platelet count. It is suggested that the index of suspicion for malaria should be kept high in patients presenting with fever associated Anemia and thrombocytopenia.
Authors and Affiliations
Dr. Akhil Gupta
Keywords
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