Study of Mean Platelet Volume in patients of Acute Myocardial Infarction
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Acute myocardial infarction is a common disease with serious consequences in mortality, morbidity, and cost to the society. Coronary atherosclerosis plays a pivotal part as the underlying substrate in many patients. Mean platelet volume (MPV)is a measure of platelet size, generated by full blood count analyzers as part of the routine complete blood count test cycle. An increased MPV, as an indicator of larger, more reactive platelets resulting from an increased platelet turnover, may therefore represent a risk factor for overall vascular mortality, including myocardial infarction. The objective of this study is find out Mean platelet volume (MPV) in AMI cases and compare them with age- and gender-matched controls, and to see correlation of MPV with established (Traditional) risk factors for AMI. Conclusion of study is that MPV is a very low cost investigation and can be obtained easily in most health care settings. This study corroborates others observations that MPV is higher in patients with AMI. It is not yet clear whether increase in MPV is the cause or effect of coronary artery occlusion. However we propose that it may be useful as a marker of myocardial infarction in an appropriate clinical situation.
Authors and Affiliations
Dr Yogendra Malhotra, Dr. Badal Binkar
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