The Multifaceted Effects of Vitamin D and Its Potential Contribution to Rheumatoid Arthritis
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 8
Abstract
Vitamin D (VD) is known to have pleiotropic effects on various tissues and organs including those of the immune and musculoskeletal systems. VD deficiency has been suggested to trigger the onset of autoimmune diseases including rheumatoid arthritis (RA), although the significance of this finding remains controversial. Conversely, patients with RA often have VD deficiency, and it may modify the pathophysiology of the disorder. This review summarizes recent findings on the multiple roles of VD that may modulate the clinical course of RA. The possibility of administering VD as a therapeutic option for RA is also explored.
Authors and Affiliations
Kayo Masuko
Keywords
Related Articles
- EP ID EP348596
- DOI 10.9734/BJMMR/2014/7647
- Views 55
- Downloads 0
Study of the Hormones Controlling Food Intake (Leptin and Agouti Related Protein “AgRP”) in Cannabis Smokers
Background: Leptin is an adipocyte derived hormone which is thought to be a key regulator of food intake and body weight. Agouti-related protein also called Agouti-related peptide (AgRP) is a neuropeptide produced in the...
Nurse leaders’ Attitudes, Self-Efficacy and training Needs for Implementing Evidence-Based Practice: Is It Time for a Change toward Safe Care?
Introduction: Evidence-based practice (EBP) has been recognized as the gold standard for safe and high quality care. Nurse leaders have a strategic position in terms of initiating changes in clinical settings for success...
Is Human Immunodeficiency Virus Still Transmissible Through Blood Transfusion in Children with Sickle Cell Anaemia in Jos, Nigeria?
Aims: To compare the prevalence of HIV infection amongst transfused and non-transfused children with sickle cell anaemia (SCA) in Jos, Nigeria and explore the factors affecting it. Study Design: This was a prospective ca...
Prognostic Implications of Expression of the Wilms Tumor 1 (WT1) Gene in Acute Leukemia (Experience from South Egypt)
Background: Wilms’ tumor (WT1) gene expression has been reported in the majority of acute leukemia patients at diagnosis and has been evaluated as a prognostic and minimal residual disease (MRD) marker but its role is st...
Diabetic Foot Ulcers: Epidemiology, Management Modalities and Outcome at Benue State University Teaching Hospital Makurdi
Aim: To determine the epidemiology of diabetic foot ulcers (DFU), types, and the risk factors associated with their development at Benue State University Teaching Hospital, Makurdi Nigeria. To assess outcome of various m...