Usefulness of Serum Prolactin in Differentiating Epileptic and Pseudoseizures in Children
Journal Title: People's Journal of Scientific Research. - Year 2013, Vol 6, Issue 1
Abstract
Transient hyperprolectinemia has been reported to follow unprovoked seizures. This study was conducted in 90 children aged 1-18 years of age. The study comprised of four groups: Group-1 consisted of children with epilepsy which was further subdivided into GTCS, CPS and SPS. Group-2 comprised of children having febrile convulsions. Group-3 comprised of children suffering from non-epileptic paroxysmal events like breath holding spell, syncope and pseudoseizures or conversion reaction. Group-4 consisted of children who served as controls. Blood sample was collected within two hours of the event in all the groups. The exact interval between the event and the collection of blood sample was noted. Serum prolactin level was estimated by ELISA technique. In the present study, significant elevation of serum prolactin level was observed only in the Group-1 (28.77+15.49ng/ml) as compared to controls (9.53+2.45ng/ml) and the highest levels were observed in children with GTCS. Maximum elevation of prolactin was seen within 15 to 30 minutes post ictally. As the prolactin levels become normal after two hours of post ictal period, the test looses its significance.
Authors and Affiliations
Om Chaurasiya, , Parul Gupta, , Anil Kaushik, , Rajesh Yadav
Keywords
Related Articles
- EP ID EP135625
- DOI -
- Views 63
- Downloads 0
The Prevalence and Pattern of Dental Caries in Pre-School Children
This study was carried out to determine the prevalence and pattern of early childhood caries and its relevant factors in pre-school children of People’s Public school of Bhopal. One hundred sixty two children aged betwee...
Actinomycotic Mycetoma of Right Foot: A Case report From Central India
Mycetoma is endemic in many developing countries. We report here a case of actinomycetoma in a 70 year old male, farmer by occupation, who presented with multiple discharging sinuses and swellings over the right foot whi...
Role of Rabeprazole on Chest Discomfort of Uncertain Origin
Chest discomfort is a common challenge to clinicians; conditions vary from benign to life threatening. The differential diagnosis includes and overlaps cardiovascular, respiratory, gastrointestinal, usculoskeletal...
Role of Solid Lipid Nanoparticles in Augmentation of Carcinoma Therapy: An Study
amoxifen (TMX) is universally used drug for treatment of breast cancer. However, it has shown risk for development of colorectal malignancies. Hence, the present study focused on study of the effect of TM...
Liver Abscess: A Radiological cum Epidemiological Study
Liver abscess is not an uncommon disease entity. Early diagnosis and prompt interventions improve the survival and outcome of the disease. The objectives of present study were to see the common types of liver abscesses p...