Reports in Clinical Studies and Medicine

Reports in Clinical Studies and Medicine

Basic info

  • Publisher: PiscoMed Publishing
  • Country of publisher: singapore
  • Date added to EuroPub: 2020/Feb/27

Subject and more

  • LCC Subject Category: Clinical Trials, Medicine
  • Publisher's keywords: Medicine, Clinical Studies
  • Language of fulltext: english
  • Time from submission to publication: weeks

Publication charges

  • Article Processing Charges (APCs): No
  • Submission charges: No
  • Waiver policy for charges? No

Open access & licensing

  • Type of License:
  • License terms
  • Open Access Statement: No
  • Year open access content began: 2019
  • Does the author retain unrestricted copyright? False
  • Does the author retain publishing rights? False

Best practice polices

  • Permanent article identifier:
  • Content digitally archived in:
  • Deposit policy registered in:

This journal has '8' articles

Detection of HBV DNA by PCR and its application in clinical transfusion

Detection of HBV DNA by PCR and its application in clinical transfusion

Authors: Shunqing Li
Year: 2019, Volume: 1, Number: 1
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Abstract

This study was to detect the hepatitis B virus (HBV) DNA copies in patients through blood transfusions; recessive carriers with HBsAg negative but HBV DNA positive were further studied to see the content and distribution of HBV in patients, and provide evidence for the clinical treatment. A total of 532 blood samples collected from July 2014 to July 2015 were tested for HBV-DNA viral load and hepatitis B serological markers using quantitative Polymerase Chain Reaction (qPCR) and serologic test (five serological markers of hepatitis B). The results showed that, 3 cases were HBV serology negative and the HBV-DNA viral load was in the range of 250-500 whereas only 1 case was HBsAb positive and the HBV-DNA viral load was above 500. qPCR, for detecting HBV DNA, together with serological routine test can effectively reduce HBV infection during transfusion and prevent medical disputes.

Keywords: Hepatitis B virus, HBsAg, serological markers, screening
Clinical application of minimal invasive arthroscope on patella fracture surgery

Clinical application of minimal invasive arthroscope on patella fracture surgery

Authors: Bo Jiang, Lele Liao
Year: 2019, Volume: 1, Number: 1
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Abstract

The aim of the research is to perform the application of minimal invasive arthroscope on patella fracture surgery. A total of 100 patients with the cases of patella fracture were selected from our hospital and the Second Xiangya Hospital’s Orthopaedic Ward. These patients were divided into ‘Observation Group’ and ‘Comparison Group’. The former was treated with traditional open surgery whereas the latter used the arthroscopic surgery. The postsurgical score indicated statistically significant differences (P < 0.05) in the Lysholm Knee and Oswestry Low Back pain scale. By performing arthroscopic surgery on patella fractures, the patients’ recovery was accelerated while the pain was greatly reduced, which in turn, improved the quality of patients’ life and provided valuable clinical value.

Keywords: Arthroscope; Patella fracture; Pain scoring
Clinical study of endoscopic mucosal resection for digestive tract early cancer and precancerous lesions treatment

Clinical study of endoscopic mucosal resection for digestive tract early cancer and precancerous lesions treatment

Authors: Huiji Peng
Year: 2019, Volume: 1, Number: 1
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Abstract

The clinical effect of endoscopic mucosal resection (EMR) on the digestive tract of early cancer and precancerous lesions was analyzed. 63 patients with early gastrointestinal cancer and precancerous lesions treated in our hospital from January 2013 to May 2015 were recruited for this study. Patients were randomly divided into the observation group (32 cases) and the control group (31 cases). The control group underwent conventional surgical treatment, while the observation group underwent EMR. Both groups were observed for the clinical effect. The curative resection rate was 100.0% (P > 0.05). The postoperative complication rate was 3.1% (1/32) in the observation group and 25.8% (8/31) in the control group. The operation time for the observation group was significantly shorter than the control group (P < 0.05). Subjects were followed up for 1 year. Both groups showed no primary tumor metastasis and recurrence (P > 0.05). EMR treatment showed good effect and significantly fewer complications in patients.

Keywords: Endoscopic mucosal resection; Early gastrointestinal cancer; Precancerous lesion
Clinical effect of combined anterior and posterior approach surgery for cervical spondylotic myelopathy

Clinical effect of combined anterior and posterior approach surgery for cervical spondylotic myelopathy

Authors: Yanzhou Jiang, Lianchong Fu and Yunshan Mu
Year: 2019, Volume: 1, Number: 1
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Abstract

Objective: To evaluate the clinical efficacy of combined anterior and posterior approach surgery for patients with spinal type. Methods: 96 patients with cervical spondylosis were randomly selected among all patients admitted in our hospital from January 2013 to December 2015. They were evenly assigned to A, B or C group, 32 patients each. Patients in Group A suffered from cervical myelopathy and were treated by combined anterior and posterior approach. Patients in Group B group suffered from cervical vertebra disease and accepted a cervical corpectomy decompression and a bone graft fusion internal fixation surgery. Patients in Group C accepted conventional posterior decompression and fusion surgery for lateral mass screw fixation. Postoperative follow-up, X-ray intervertebral stability and fusion, neurological function JOA score and clinical efficacy of the effective date were compared. Results: JOA scores of all three groups were improved after 6 months. After a year, patients in Group A, B and C scored (16.3 ± 1.83), (15.7 ± 1.15) and (15.59 ± 1.21), respectively. The pairwise score differences between any two groups were statistically significant (P < 0.05). After one year’s follow-up, the bone graft and internal fixation material had no signs of loosening, displacement or subsidence. The fusion rates of Group A, B and C reached 90.6%, 53.1% and 56.25%, respectively. Similarly, the pairwise differences in fusion rate between any two groups were statistically significant (P < 0.05). The clinical effectiveness was classified as apparent, effective, fair and invalid. The effective rates of Group A, B and C were 87.5%, 50% and 56.2%, respectively. The pairwise differences between any two groups were statistically significant (P < 0.05). Conclusion: Combined anterior and posterior approach surgery significantly improved the clinical efficacy than the other two surgeries.

Keywords: Anterior and posterior surgery combined therapy; Spinal cord type of cervical spondylosis; Clinical efficacy; Spinal nerve function
Clinical analysis of ureteroscopic holmium laser lithotripsy for the treatment of nephrolithiasis

Clinical analysis of ureteroscopic holmium laser lithotripsy for the treatment of nephrolithiasis

Authors: Yansi Xue, Lei Xu, Xiaojun Xu, Dukun Wang, Guocheng Wang, Yi Chen
Year: 2019, Volume: 1, Number: 1
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Abstract

The objective of the study is to evaluate the clinical value of ureteroscopic holmium laser lithotripsy for the treatment of nephrolithiasis. Clinical data of 44 patients treated for renal stones with polyscope modular flexible ureteroscopic holmium laser lithotripsy from May 2014 to April 2015 were retrospectively analysed. Following the operation, F4.7 D-J stents were routinely indwelled for 4 weeks and catheterization for 1-3 days. A plain kidney, ureter, and bladder (KUB) X-ray was performed on postoperative days too. A total of four success cases were determined following the first treatment. The remaining 40 cases were first placed with double-J stent and the surgery was performed one week later. Stone sizes between 0.8-4.0 cm in diameter were defined. The operation time for the treatment was 80-180 minutes. Patients were discharged within 3-5 days, and the double-J stent was removed within 1-3 months. 39 patients were found to be completely stone-free at approximately three months postoperatively. However, five patients were shown to have 11.1% of residual stones after treatment. No blood transfusion, septic shock, ureteral injury, or other complications were reported. Flexible ureteroscopic holmium laser lithotripsy is safe and effective for the treatment of nephrolithiasis. This approach could be a valuable choice for the treatment of patients with renal stones.

Keywords: Ureteroscopic holmium laser lithotripsy; Renal stone
Causes and management of bleeding during laparoscopic colorectal cancer surgery

Causes and management of bleeding during laparoscopic colorectal cancer surgery

Authors: Ming Xu, Weiqiang Wu, Zengqiang Yang, Feng Gao
Year: 2019, Volume: 1, Number: 1
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Abstract

In this paper, the causes of bleeding during laparoscopic colorectal surgery and the measures to solve it are discussed. 386 cases of laparoscopic colorectal cancer surgery in our hospital from January to December 2015 were selected. There were 17 cases of bleeding during surgery, which accounted for 4.4% of the total amount. 2 cases were converted to laparotomy, and 15 cases were surgery via laparoscopy. In the surgical process, improper surgery, lack of good laparoscopic anatomical structure of the cognitive level, and congenital anatomic variation may have caused the accidental bleeding during surgery. Corresponding measures should be taken to stop accidental bleeding.

Keywords: Laparoscope; Colorectal cancer surgery; Causes of bleeding; Processing strategy
Diagnosing ovarian masses by using nuclear magnetic resonance

Diagnosing ovarian masses by using nuclear magnetic resonance

Authors: Erning Zhang
Year: 2019, Volume: 1, Number: 1
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Abstract

In the research, nuclear magnetic resonance (NMR) was used to study and diagnose ovarian tumour. A total of 80 ovarian tumour patients who were admitted to the hospital from February 2014 to May 2016 were selected and randomly divided into 2 groups, 40 in the case group and 40 in the control group. The case group used NMR whereas the control group utilized B-mode ultrasound to compare the characteristics of tumor masses, accuracy, sensitivity, and specificity of the clinical diagnosis afterwards. The accuracy, sensitivity, specificity, and characteristics of tumour masses by NMR were 95.84%, 94.75%, 90.92%, and 100%, respectively, which were apparently higher than those of the B-mode ultrasound scanning (64.28%, 77.78%, 75.08%, and 70.83%, respectively). Difference of each index among the four between the two methods was statistically significant (p < 0.05). Therefore, NMR is superior to ultrasound in diagnosing ovarian tumour.

Keywords: Nuclear magnetic resonance; Ovarian tumour; Clinical diagnosis
Research and analysis for cancerous perianal disease

Research and analysis for cancerous perianal disease

Authors: Chentai Yu, Hongyu Chen, Xiaodong Jiang, Tangxue Gui
Year: 2019, Volume: 1, Number: 1
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Abstract

Objective: To analyze cancerous perianal disease. This study summed up the effective measures for prevention and treatment of perianal cancer patients. Methods: Twelve perianal cancer patients were recruited from June 2011 to June 2016. Retrospective analysis was carried out for the 12 patients about the causes and effective treatment. Results: Hemorrhoids cancer was found in 6 cases: only two received proper treatment; one had metastasis and received chemotherapy; 1 had good prognosis after colon diversion; two were discharged from hospital and received conservative treatment, which were ineffective and worsened the condition. Fistula cancer was found in 2 cases: one received surgery and one gave up treatment. Anal cancer was found in 2 cases: both received surgery. Perianal skin squamous cell carcinoma was found in 1 case, which ended up with the transfer to another hospital. Perianal melanoma was found in 1 case: patient was hospitalized due to perianal neoplasm; then histopathology confirmed melanoma and patient gave up for treatment. Conclusion: Perianal cancer affects the quality of life and health of patients. The relevant medical institutions must actively take measures against the perianal cancer, which has significant improvement to the survival of patients.

Keywords: Perianal disease; Cancer; Treatment; Prevention

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