Resistance to the Translation Initiation Inhibitor Silvestrol is Mediated by ABCB1/P-Glycoprotein Overexpression in Acute Lymphoblastic Leukemia Cells Journal title: The AAPS Journal Authors: Sneha V. Gupta, Ellen J. Sass, Melanie E. Davis, Ryan B. Edwards, Gerard Lozanski, Nyla A. Heerema,... Subject(s): Medicine
Role of Cannabinoids in the Development of Fatty Liver (Steatosis) Journal title: The AAPS Journal Authors: Vishnudutt Purohit, Rao Rapaka, David Shurtleff Subject(s): Medicine
Targeting Fatty Acid Amide Hydrolase (FAAH) to Treat Pain and Inflammation Journal title: The AAPS Journal Authors: Joel E. Schlosburg, Steven G. Kinsey, Aron H. Lichtman Subject(s): Medicine
Prediction of Hepatic Clearance in Human From In Vitro Data for Successful Drug Development Journal title: The AAPS Journal Authors: Masato Chiba, Yasuyuki Ishii, Yuichi Sugiyama Subject(s): Medicine
Technical Pitfalls and Improvements for High-speed Screening and QSAR Analysis to Predict Inhibitors of the Human Bile Salt Export Pump (ABCB11/BSEP) Journal title: The AAPS Journal Authors: Hikaru Saito, Masako Osumi, Hiroyuki Hirano, Wangsoo Shin, Ryota Nakamura, Toshihisa Ishikawa Subject(s): Medicine
Mechanism-Based Pharmacokinetic Modeling to Evaluate Transporter-Enzyme Interplay in Drug Interactions and Pharmacogenetics of Glyburide Journal title: The AAPS Journal Authors: Manthena V. S. Varma, Renato J. Scialis, Jian Lin, Yi-An Bi, Charles J. Rotter, Theunis C. Goosen, X... Subject(s): Medicine
Searching for polymorphisms that affect gene expression and mRNA processing: Example ABCB1 (MDR1) Journal title: The AAPS Journal Authors: Danxin Wang, Wolfgang Sadée Subject(s): Medicine
Conformational characteristics of the interaction of SR141716A with the CB1 cannabinoid receptor as determined through the use of conformationally constrained analogs Journal title: The AAPS Journal Authors: Brian F. Thomas, Yanan Zhang, Marcus Brackeen, Kevin M. Page, S. Wayne Mascarella, Herbert H. Seltzm... Subject(s): Medicine
Endocannabinoid mechanisms of pain modulation Journal title: The AAPS Journal Authors: Andrea G. Hohmann, Richard L. Suplita Subject(s): Medicine
Cetirizine from topical phosphatidylcholine-hydrogenated liposomes: Evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model Journal title: The AAPS Journal Authors: Abeer A. W. Elzainy, Xiaochen Gu, F. Estelle R. Simons, Keith J. Simons Subject(s): Medicine
The role of halogen substitution in classical cannabinoids: A CB1 pharmacophore model Journal title: The AAPS Journal Authors: Spyros P. Nikas, Jolanta Grzybowska, Demetris P. Papahatjis, Avgui Charalambous, Ali R. Banijamali,... Subject(s): Medicine
Hydroxyzine from topical phospholipid liposomal formulations: Evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model Journal title: The AAPS Journal Authors: Abeer A W Elzainy, Xiaochen Gu, F. Estelle R. Simons, Keith J. Simons Subject(s): Medicine
Design and synthesis of the CB1 selective cannabinoid antagonist AM281: A potential human SPECT ligand Journal title: The AAPS Journal Authors: Ruoxi Lan, Qian Lu, Pusheng Fan, John Gatley, Nora D. Volkow, Susanthi R. Fernando, Roger Pertwee, A... Subject(s): Medicine
Fabrication and In Vitro/In Vivo Performance of Mucoadhesive Electrospun Nanofiber Mats Containing α-Mangostin Journal title: AAPS PharmSciTech Authors: Wipada Samprasit, Theerasak Rojanarata, Prasert Akkaramongkolporn, Tanasait Ngawhirunpat, Ruchadapor... Subject(s): Medicine
Development and Characterization of Lyophilized Diazepam-Loaded Polymeric Micelles Journal title: AAPS PharmSciTech Authors: Jiraphong Suksiriworapong, Tanaporn Rungvimolsin, Atitaya A-gomol, Varaporn Buraphacheep Junyapraser... Subject(s): Medicine