Synthesis and Antioxidant Activity of Mixed Ligand Complex of Quercetin and Aspartic Acid with Cobalt(II)
The Value of Programmed Death Ligand 1 Expression in Cancer Patients Treated with Neoadjuvant Chemotherapy Journal title: Sultan Qaboos University Medical Journal Authors: Malika Al-Dughaishi, Asem Shalaby, Khawla Al-Ribkhi, Ammar Boudaka, Mohamed-Rachid Boulassel, Jumana... Subject(s): Medicine, Biochemistry, Biomedicine
FasL gene knock-down therapy enhances the antiglioma immune response Journal title: Neuro-Oncology Authors: Timothy Jansen, Betty Tyler, Joseph L. Mankowski, Violette Renard Recinos, Gustavo Pradilla, Federic... Subject(s): Medicine
Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development Journal title: The AAPS Journal Authors: Darshana Jani, John Allinson, Flora Berisha, Kyra J. Cowan, Viswanath Devanarayan, Carol Gleason, An... Subject(s): Medicine
Ligand-Binding Assay Development: What Do You Want to Measure Versus What You Are Measuring? Journal title: The AAPS Journal Authors: Andrew P. Mayer, Charles S. Hottenstein Subject(s): Medicine
Emerging Technologies to Increase Ligand Binding Assay Sensitivity Journal title: The AAPS Journal Authors: Saloumeh K. Fischer, Alison Joyce, Mark Spengler, Tong-Yuan Yang, Yao Zhuang, Marianne Scheel Fjordi... Subject(s): Medicine
Calculations for Adjusting Endogenous Biomarker Levels During Analytical Recovery Assessments for Ligand-Binding Assay Bioanalytical Method Validation Journal title: The AAPS Journal Authors: John F. Marcelletti, Cindy L. Evans, Manju Saxena, Adriana E. Lopez Subject(s): Medicine
Workshop Report: AAPS Workshop on Method Development, Validation, and Troubleshooting of Ligand-Binding Assays in the Regulated Environment Journal title: The AAPS Journal Authors: Marian Kelley, Lauren Stevenson, Michaela Golob, Viswanath Devanarayan, Joao Pedras-Vasconcelos, Rol... Subject(s): Medicine
Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled Receptors Journal title: The AAPS Journal Authors: Zhiwei Feng, Guanxing Hu, Shifan Ma, Xiang-Qun Xie Subject(s): Medicine
Measurement of Free Versus Total Therapeutic Monoclonal Antibody in Pharmacokinetic Assessment is Modulated by Affinity, Incubation Time, and Bioanalytical Platform Journal title: The AAPS Journal Authors: Jeffrey J. Talbot, Dominador Calamba, Melody Pai, Mark Ma, Theingi M. Thway Subject(s): Medicine
Mechanistic Pharmacokinetic/Target Engagement/Pharmacodynamic (PK/TE/PD) Modeling in Deciphering Interplay Between a Monoclonal Antibody and Its Soluble Target in Cynomolgus Monkeys Journal title: The AAPS Journal Authors: Weirong Wang, Xiaofeng Wang, Rajitha Doddareddy, Damien Fink, Thomas McIntosh, Hugh M. Davis, Honghu... Subject(s): Medicine
Formation of Activity Cliffs Is Accompanied by Systematic Increases in Ligand Efficiency from Lowly to Highly Potent Compounds Journal title: The AAPS Journal Authors: Antonio de la Vega de León, Jürgen Bajorath Subject(s): Medicine
Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing Journal title: The AAPS Journal Authors: Hongyan Li, Robert Ortiz, Linh T. B. Tran, Hossein Salimi-Moosavi, Jennifer Malella, Christopher A.... Subject(s): Medicine
Theoretical Considerations and Practical Approaches to Address the Effect of Anti-drug Antibody (ADA) on Quantification of Biotherapeutics in Circulation Journal title: The AAPS Journal Authors: Marian Kelley, Ago B. Ahene, Boris Gorovits, John Kamerud, Lindsay E. King, Thomas McIntosh, Jihong... Subject(s): Medicine
Ligand-Binding Assays in the 21st Century Laboratory: Recommendations for an Automated Data Interchange Process Journal title: The AAPS Journal Authors: Sheldon S. Leung, Joel Usansky, Robert Lynde, Theingi Thway, Robert Hendricks, David Rusnak Subject(s): Medicine