Ligand-Binding Assay Development: What Do You Want to Measure Versus What You Are Measuring? Journal title: The AAPS Journal Authors: Andrew P. Mayer, Charles S. Hottenstein Subject(s): Medicine
Calculations for Adjusting Endogenous Biomarker Levels During Analytical Recovery Assessments for Ligand-Binding Assay Bioanalytical Method Validation Journal title: The AAPS Journal Authors: John F. Marcelletti, Cindy L. Evans, Manju Saxena, Adriana E. Lopez Subject(s): Medicine
Workshop Report: AAPS Workshop on Method Development, Validation, and Troubleshooting of Ligand-Binding Assays in the Regulated Environment Journal title: The AAPS Journal Authors: Marian Kelley, Lauren Stevenson, Michaela Golob, Viswanath Devanarayan, Joao Pedras-Vasconcelos, Rol... Subject(s): Medicine
Theoretical Considerations and Practical Approaches to Address the Effect of Anti-drug Antibody (ADA) on Quantification of Biotherapeutics in Circulation Journal title: The AAPS Journal Authors: Marian Kelley, Ago B. Ahene, Boris Gorovits, John Kamerud, Lindsay E. King, Thomas McIntosh, Jihong... Subject(s): Medicine
Ligand-Binding Assays in the 21st Century Laboratory: Recommendations for an Automated Data Interchange Process Journal title: The AAPS Journal Authors: Sheldon S. Leung, Joel Usansky, Robert Lynde, Theingi Thway, Robert Hendricks, David Rusnak Subject(s): Medicine
Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of Drug Development Journal title: The AAPS Journal Authors: Jean W. Lee, Marian Kelley, Lindsay E. King, Jihong Yang, Hossein Salimi-Moosavi, Meina T. Tang, Jia... Subject(s): Medicine
Ligand-Binding Mass Spectrometry to Study Biotransformation of Fusion Protein Drugs and Guide Immunoassay Development: Strategic Approach and Application to Peptibodies Targeting the Thrombopoietin Receptor Journal title: The AAPS Journal Authors: Michael P. Hall, Colin Gegg, Kenneth Walker, Christopher Spahr, Robert Ortiz, Vimal Patel, Steven Yu... Subject(s): Medicine
Appropriate calibration curve fitting in ligand binding assays Journal title: The AAPS Journal Authors: John W. A. Findlay, Robert F. Dillard Subject(s): Medicine
Systematic Verification of Bioanalytical Similarity Between a Biosimilar and a Reference Biotherapeutic: Committee Recommendations for the Development and Validation of a Single Ligand-Binding Assay to Support Pharmacokinetic Assessments Journal title: The AAPS Journal Authors: Joseph C. Marini, Michael Anderson, Xiao-Yan Cai, John Chappell, Todd Coffey, Dominique Gouty, Aparn... Subject(s): Medicine
