ADME of Biologics—What Have We Learned from Small Molecules? Journal title: The AAPS Journal Authors: Thomayant Prueksaritanont, Cuyue Tang Subject(s): Medicine
Monoamine Transporter Structure, Function, Dynamics, and Drug Discovery: A Computational Perspective Journal title: The AAPS Journal Authors: Sankar Manepalli, Christopher K. Surratt, Jeffry D. Madura, Tammy L. Nolan Subject(s): Medicine
Human Cannabinoid 1 GPCR C-Terminal Domain Interacts with Bilayer Phospholipids to Modulate the Structure of its Membrane Environment Journal title: The AAPS Journal Authors: Elvis K. Tiburu, Sergiy Tyukhtenko, Han Zhou, David R. Janero, Jochem Struppe, Alexandros Makriyanni... Subject(s): Medicine
Small Molecule Modifiers of the microRNA and RNA Interference Pathway Journal title: The AAPS Journal Authors: Alexander Deiters Subject(s): Medicine
Structure-Based Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes Journal title: The AAPS Journal Authors: Haiyan Li, Jin Sun, Xiaofan Sui, Zhongtian Yan, Yinghua Sun, Xiaohong Liu, Yongjun Wang, Zhonggui He Subject(s): Medicine
Prediction of Biliary Excretion in Rats and Humans Using Molecular Weight and Quantitative Structure–Pharmacokinetic Relationships Journal title: The AAPS Journal Authors: Xinning Yang, Yash A. Gandhi, David B. Duignan, Marilyn E. Morris Subject(s): Medicine
Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively? Journal title: The AAPS Journal Authors: Jayaraj Ravindran, Sahdeo Prasad, Bharat B. Aggarwal Subject(s): Medicine
Prediction of Solubility and Permeability Class Membership: Provisional BCS Classification of the World’s Top Oral Drugs Journal title: The AAPS Journal Authors: Arik Dahan, Jonathan M. Miller, Gordon L. Amidon Subject(s): Medicine
Key elements of bioanalytical method validation for macromolecules Journal title: The AAPS Journal Authors: Marian Kelley, Binodh DeSilva Subject(s): Medicine
Commentary: Where and how could biomarkers be used in 2016 Journal title: The AAPS Journal Authors: M. J. Finley Austin, Lee Babiss Subject(s): Medicine
Small Molecule Specific Run Acceptance, Specific Assay Operation, and Chromatographic Run Quality Assessment: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Teams Journal title: The AAPS Journal Authors: Eric J. Woolf, Stuart McDougall, Douglas M. Fast, Maristela Andraus, Matthew Barfield, Michael Black... Subject(s): Medicine
An Electrically Tight In Vitro Blood–Brain Barrier Model Displays Net Brain-to-Blood Efflux of Substrates for the ABC Transporters, P-gp, Bcrp and Mrp-1 Journal title: The AAPS Journal Authors: Hans Christian Helms, Maria Hersom, Louise Borella Kuhlmann, Lasina Badolo, Carsten Uhd Nielsen, Bir... Subject(s): Medicine
Bioanalytical Method Validation: Concepts, Expectations and Challenges in Small Molecule and Macromolecule—A Report of PITTCON 2013 Symposium Journal title: The AAPS Journal Authors: Edward D. Bashaw, Binodh DeSilva, Mark J. Rose, Yow-Ming C. Wang, Chinmay Shukla Subject(s): Medicine
Many Approved Drugs Have Bioactive Analogs With Different Target Annotations Journal title: The AAPS Journal Authors: Ye Hu, Eugen Lounkine, Jürgen Bajorath Subject(s): Medicine
Validation of a Ligand Binding Assay Using Dried Blood Spot Sampling Journal title: The AAPS Journal Authors: Daniel Burns, Laura Brunner, Surendran Rajendran, Beth Johnson, Mark Ma, Jin Wang Subject(s): Medicine