Pharmacodynamic Model of Sodium–Glucose Transporter 2 (SGLT2) Inhibition: Implications for Quantitative Translational Pharmacology Journal title: The AAPS Journal Authors: Tristan S. Maurer, Avijit Ghosh, Nahor Haddish-Berhane, Aarti Sawant-Basak, Carine M. Boustany-Kari,... Subject(s): Medicine
Bilirubin—A Potential Marker of Drug Exposure in Atazanavir-Based Antiretroviral Therapy Journal title: The AAPS Journal Authors: Dinko Rekić, Oskar Clewe, Daniel Röshammar, Leo Flamholc, Anders Sönnerborg,... Subject(s): Medicine
Population Pharmacokinetics of Telapristone (CDB-4124) and its Active Monodemethylated Metabolite CDB-4453, with a Mixture Model for Total Clearance Journal title: The AAPS Journal Authors: Denise Morris, Joseph Podolski, Alan Kirsch, Ronald Wiehle, Lawrence Fleckenstein Subject(s): Medicine
Factors Influencing the Use and Interpretation of Animal Models in the Development of Parenteral Drug Delivery Systems Journal title: The AAPS Journal Authors: Marilyn N. Martinez Subject(s): Medicine
Holford NHG and Sheiner LB “Understanding the Dose-Effect Relationship-Clinical Application of Pharmacokinetic-Pharmacodynamic Models”, Clin Pharmacokin 6:429–453 (1981)—The Backstory Journal title: The AAPS Journal Authors: Nick Holford Subject(s): Medicine
Comparison of Two Pharmacodynamic Transduction Models for the Analysis of Tumor Therapeutic Responses in Model Systems Journal title: The AAPS Journal Authors: Jun Yang, Donald E. Mager, Robert M. Straubinger Subject(s): Medicine
Biodistribution Mechanisms of Therapeutic Monoclonal Antibodies in Health and Disease Journal title: The AAPS Journal Authors: Mohammad Tabrizi, Gadi Gazit Bornstein, Hamza Suria Subject(s): Medicine
A History of Biopharmaceutics in the Food and Drug Administration 1968–1993 Journal title: The AAPS Journal Authors: Jerome Philip Skelly Subject(s): Medicine
Mechanistic Toxicokinetic Model for γ-Hydroxybutyric Acid: Inhibition of Active Renal Reabsorption as a Potential Therapeutic Strategy Journal title: The AAPS Journal Authors: Melanie A. Felmlee, Qi Wang, Dapeng Cui, Samuel A. Roiko, Marilyn E. Morris Subject(s): Medicine
Use of Dried Blood Spots in Drug Development: Pharmacokinetic Considerations Journal title: The AAPS Journal Authors: Malcolm Rowland, Gary T. Emmons Subject(s): Medicine
Application of Quantitative Pharmacology in Development of Therapeutic Monoclonal Antibodies Journal title: The AAPS Journal Authors: Mohammad Tabrizi, Cherryl Funelas, Hamza Suria Subject(s): Medicine
Prediction of Exposure–Response Relationships to Support First-in-Human Study Design Journal title: The AAPS Journal Authors: John P. Gibbs Subject(s): Medicine
Development of a Population Pharmacokinetic Model for Taranabant, a Cannibinoid-1 Receptor Inverse Agonist Journal title: The AAPS Journal Authors: Xiujiang (Susie) Li, Jace Nielsen, Brenda Cirincione, Hankun Li, Carol Addy, John Wagner, Alan Hartf... Subject(s): Medicine
A Novel Ultrasensitive Hybridization-Based ELISA Method for 2-Methoxyphosphorothiolate MicroRNAs and Its In vitro and In vivo Application Journal title: The AAPS Journal Authors: Kenneth K. Chan, Zhongfa Liu, Zhiliang Xie, Ming Chiu, Hongyan Wang, Ping Chen, Sarah Dunkerson, Mic... Subject(s): Medicine
Pharmacokinetics of Anti-hepcidin Monoclonal Antibody Ab 12B9m and Hepcidin in Cynomolgus Monkeys Journal title: The AAPS Journal Authors: Jim J. Xiao, Wojciech Krzyzanski, Yow-Ming Wang, Hongyan Li, Mark J. Rose, Mark Ma, Yuling Wu, Beth... Subject(s): Medicine