PREPARATION AND CHARACTERIZATION OF TOLTERODINE TARTRATE PRONIOSOMES
Journal Title: Universal Journal of Pharmaceutical Research - Year 2017, Vol 2, Issue 2
Abstract
The present work deals with the preparation of Tolterodine tartrate proniosome formulations by ether injection method by using different surfactants in different ratios. The prepared proniosomal formulation were evaluated for vesicle size, rate of spontaneity, encapsulation efficiency, drug content etc. In vitro release study was conducted and it indicated that, increases in liphophilicity of surfactants decreases release of Tolterodine tartrate from proniosomal formulations. Stability studies were performed at optimized formulation PG4, indicated that, the prepared formulations remain stable at room and refrigeration temperature.
Authors and Affiliations
Adim Ekene Ugochukwu, Obeta Judith Nnedimkpa, Ngwu Ogochukwu Rita
Keywords
Related Articles
- EP ID EP36381
- DOI https://doi.org/10.22270/ujpr.v2i2.R1
- Views 282
- Downloads 0
Editorial.
It is great honor and privilege for me to be appointed as Member - Editorial Board, Universal Journal of Pharmaceutical Research (UJPR). My heartiest salutations to Prof. Dr. Kapil Kumar, Editor-in-Chief and the other bo...
BUCCAL DRUG DELIVERY SYSTEM: A TOOL FOR THE EFFECTIVE DELIVERY OF PHARMACEUTICALS
The Buccal drug delivery system includes drug administration through the buccal mucosa, mainly composed of the lining of the cheeks. Buccal drug delivery system provides a convenient route of administration for both syst...
EpCAM- AN OLD CANCER ANTIGEN, TURNED ONCOGENIC RECEPTOR AND ITS TAGETING IMMUNOTHERAPY
EpCAM is a cell adhesion molecule. Its structure, its expression and the oncogenic potential, and its signaling network and target therapy were in concise reviewed. In recent advances,in addition to PI3K/akt and Raf/MAPK...
DEVELOPMENT AND CHARACTERIZATION OF MUCOADHESIVE PATCHES FOR BUCCAL DELIVERY OF PREGABALIN
Pregabalin is a structural analogue of the inhibitory neurotransmitter γ-amino butyric acid (GABA) having short half-life (5-6 hrs) and is used in the management of epilepsy. The aim of this study was to prepare a buccal...
THE IMPACT OF HOSPITAL INFORMATION SYSTEM ON THE WORKING PROCESS OF IMAM JA’FAR SADIQ HOSPITAL, ALBORZ PROVINCE - 2016
This research has been done on the impact of the hospital information system on the staffing of Imam Ja’far Sadiq Hospital in Alborz in 2016. The research method is applied and in terms of data collection method, descri...