16 EFFECT OF TOTAL DOSE PARENTERAL IRON ON CARDIOVSCULAR FUNCTION IN IRON DEFICIENCY ANEMIA
Journal Title: Indian journal of applied basic medical sciences - Year 2018, Vol 20, Issue 31
Abstract
Introduction: Iron deficiency is a whole spectrum of clinical manifestation and abnormalities in the physiological functions of the body organs and tissues at rest or during stress, primarily or secondarily to iron deficiency. IJABMS JULY 2018 Material and Methods: This study was conducted at a tertiary care hospital. A group of thirty five patients of iron deficiency anaemia who had a baseline change in their ECGs were selected. Iron deficiency anaemia was defined as haemoglobin< 10g/dl with a ferritin level of <30µg/L. The patients were then given the required total parenteral iron dose in the form of iron sucrose. Results: The study noted a significant improvement in electrocardiogram of the patients. Twenty one of the thirty five patients had a normalization of their ECGs with best results seen with juvenile pattern, followed by occasional VPCs and ST-T changes showing the least improvement. Discussion: An improvement was noted in ejection fractions the patients with a low ejection fraction compared to those with a higher ejection fraction. The study noted a significant improvement in the complaints such as fatigue, leg cramps and menorrhagia. Conclusion: All these changes were however not associated with a significant increase in haemoglobin levels, thereby showing that iron per se has a significant role in the integrity of the cardiovascular system as well as in the metabolism of the cells in general.
Authors and Affiliations
Dr Paltial N Palat
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