2: STUDY OF RELATIONSHIP BETWEEN SERUM CALCIUM & ARTERIAL BLOOD PRESSURE IN PATIENTS WITH HYPERTENSION .
Journal Title: Indian journal of applied basic medical sciences - Year 2017, Vol 19, Issue 29
Abstract
Hypertension is the commonest cardiovascular disorder,affecting 20 % of the adult population in many countries .It is linked with coronary heart disease,stroke,congestive cardiac failure and renal dysfunction and is one of the major risk factor for cardiovascular mortality,which accounts for 20 to 50 % of all deaths.The use of calcium channel blocking agents in the treatment of hypertension shows the critical importance of calcium in the biochemical control of vascular smooth muscle tone,and thus of blood pressure homeostasis.Therefore, we designed a study to find correlation between serum calcium levels and blood pressure .50 normotensive and 50 hypertensive were studied and compared. AIMS & OBJECTIVE : To estimate serum calcium in a group of hypertensive patients and matched controls . To compare the level of serum calcium in hypertensive and normotensive control group . To study correlation between serum calcium and arterial blood pressure in hypertensive individuals . RESULT :In our study,a significant high levels of serum calcium were found in hypertensive group as compared to normotensive group(P <0.01). A statistically significant linear correlation was found between serum calcium and both systolic and diastolic blood pressure in hypertensive males (P<0.01). CONCLUSION :Our study shows a significant correlation between high serum calcium levels and high blood pressure.According to the present study,increased serum calcium leads to hypertension .Hence, serum calcium levels should be estimated in hypertensive patients .
Authors and Affiliations
Rajendra Thorat, Dr. Sachin Mulkutkar
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