23 A STUDY OF ECHOCARDIOGRAPHIC DETECTION OF CARDIAC ABNORMALITIES IN PATIENTS OF CHRONIC KIDNEY DISEASE& PROGRESSION TO HF
Journal Title: Indian journal of applied basic medical sciences - Year 2018, Vol 20, Issue 31
Abstract
Introduction: In chronic kidney disease (CKD) patients,left ventricular (LV) diastolic dysfunction occurs frequently and is associated with heart failure (HF) and higher mortality. Left ventricular systolic dysfunction is associated with coronary artery disease (CAD) and is a major determinant of prognosis. The aim of this study was to assess indices of LV diastolic dysfunction in CKD patients. Material and methods: Study included 118 CKD patients. All patients underwent transthoracic echocardiography. Diastolic function based on E and A, E/A ratio and pulmonary vein flow velocities as well as EF%, deceleration time, RA, LA volume were assessed. In dialysis patients examination was carried out before and after dialysis. Observations:In CKD patients the stage of renal failure was associated with the significant increase in LV mass, systolic LV & diastolic LV dimensions and in the size of the LA. The increase the E/E’ ratio between groups of patients was seen in this study. The reduction in deceleration time along with the decrease in estimated glomerular filtration rate was also observed in this study. Conclusions: Early identification of factors involved is necessary to prevent this devastating process. Many indexes of contractility are used and each of them has imperfections. It seems that TVI, E, E/A ratio & E/E’ ratio are good instruments for the early detection of left ventricular hypertrophy and diastolic dysfunction.
Authors and Affiliations
Dr. Pratik Modi
Keywords
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