28 CLINICO-HISTOPATHOLOGICAL STUDY OF LEPROSY PATIENTS A TERTIARY CARE HOSPITAL BASED STUDY.
Journal Title: Indian journal of applied basic medical sciences - Year 2018, Vol 20, Issue 31
Abstract
Background and Objectives: Leprosy is a chronic infectious disease caused by Mycobacterium leprae involving skin and peripheral nerves. Depending upon the immune status of the patients there are different clinico-pathological presentation. Despite having been declared eliminated in December 2005 from India as a public health problem, the prevalence of leprosy exceeds 1/10000 population in certain districts/states of India. According to 4th World Health Organization report, India accounts for 60% of the world’s new leprosy cases. This is due to stoppage of active surveillance after reaching elimination levels. A spurt in its prevalence motivated us to carry out the study. Our aim is to diagnose and typing of leprosy by histopathology and to correlate the clinical and histopathological diagnosis as per Ridley-Jopling Scale to facilitate accurate therapy. Material and methods: The prospective study was carried out in the pathology department of AMC MET Medical College, L.G. Hospital, Maninagar, Gujarat form January 2016 to December 2017, after ethical clearance from institutional ethics committee. All the punch biopsy specimens of suspected patients of leprosy were subjected to histopathological examination. Result: A total of 90 cases were studied. Among the clinically suspected cases 67 were positive for leprosy. Male to female ratio was 3.5:1, the age ranged from 4 to 80 years. Maximum cases were classified as borderline lepromatous leprosy (22) and least cases of midboderline leprosy (2) and indeterminant leprosy (2). Maximum clinico-histopathological correlation was seen in tuberculoid leprosy (100%) and indeterminant leprosy (100%). Conclusion: Combining clinical, histopathological and microbiological diagnosis of leprosy is important for proper treatment of the patient and prevention of complications.
Authors and Affiliations
Dr. Moxda S. Patel
Keywords
Related Articles
- EP ID EP533289
- DOI -
- Views 63
- Downloads 0
11 Study of Electrocardiographic changes with BMI in normal individuals
Objective: To study the electrocardiogram in asymptomatic obese young adults in the form of shift of the axis; voltage of the ECG complexes; P, QRS and T waves; PR and QT intervals; and ST segment and to assess the risk...
7 A STUDY OF DISTAL TIBIA FRACTURES TREATED WITH DISTAL TIBIA PLATE WITH OPEN REDUCTION AND MIPPO TECHNIQUE
Background: Fractures of the distal tibia can be challenging to treat because of the limited soft tissue, the subcutaneous location, and poor vascularity. There is a considerable debate regarding the best method for tre...
4 ULTRASOUND GUIDED INTERNAL JUGULAR VEIN CANNULATION IN CRITICALLY ILL PATIENTS IN ICU
Introduction: Portable ultrasound machines are highly valuable in ICUs, where a patient's condition might not permit shifting the patient to the USG department for imaging and proper positioning may be difficult due to...
11 ANTENATAL DIAGNOSIS OF PELVI-URETERIC JUNCTION OBSTRUCTION & ITS OUTCOME
Background: The term pelvic-ureteric obstruction denotes a restriction of flow of urine from the renal pelvis to the ureter which if left uncorrected will lead to progressive renal deterioration. Today majority of the ca...
1 Editorials -FOUNDATION COURSE IN UNDERGRADUATE MEDICAL CURRICULUM
In India, very few colleges had foundation courses in the true sense. Most of the colleges had one or two weeks orientation programmes before medical studies used to begin. The basic purpose was same as that of foundatio...