7 STUDY OF DYSLIPIDEMIA AND ABNORMAL LIPID PROFILE IN DIABETES MELLITUS PATIENTS AND ITS ASSOCIATION WITH INCREASED MORBIDITY.
Journal Title: Indian journal of applied basic medical sciences - Year 2018, Vol 20, Issue 31
Abstract
Introduction:Diabetes Mellitus is a heterogeneous group of metabolic disorder characterized by chronic hyperglycemia with disturbance of carbohydrate, fat and protein metabolism resulting from defect in insulin secretion, insulin action or both. The two broad categories of DM are Type 1 & Type 2. Due to paucity of dramatic symptoms, poor health awareness & the prevailing socio-economic condition type 2 diabetes frequently goes undiagnosed for many years and such patients are at increased risk of developing macro-vascular and micro-vascular complications(1). This was clearly seen in UK Prospective Diabetes Study where 50% of patients had diabetic complications at presentation (3). Lipid abnormalities play an important role in causation of diabetic atherosclerosis (4, 5) and contribute significantly to complication of diabetes. Materials & Methods: A prospective analytical study of 200 patients was undertaken at Department of Internal Medicine, AMC MET MMC Ahmedabad. Prior approval by IRB of AMC MET MMC was taken. Patients presenting to OPD were analyzed in terms of Age, Sex & Obesity related to dyslipidemia & data analyzed using Paired T test with reference study. IJABMS JULY 2018 Observations: Mean age of study population was 54 yrs. Male patients were 54.55 yrs& females were 54.80 yrs mean age. Abnormal HDL 80%, LDL 57%, VLCL 56%, Cholesterol in 37% were found. 66% of pts had BMI > 25 & were classified as obese. Conclusions: Majority of patients were 40-60 yrs age group which is a high risk age group for development of atherosclerosis & cerebrovascular events & of them >50% of pts were having altered lipid profile which is a significant risk factor for morbidities related to diabetes. Hence control of dyslipidemia in diabetics with lipid lowering agents should be given due consideration when planning a treatment regimen. KEYWORDS: Dyslipidemia, Diabetes Mellitus, Lipoproteins, Abnormal Lipid Profile.
Authors and Affiliations
Dr Ajay Rathod
Keywords
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