A brief review on cigarette induced cellular
Journal Title: International Journal of Experimental Research and Review - Year 2020, Vol 23, Issue 3
Abstract
Cigarette smoking has become one of the most common addictions in context to the present scenario of tobacco consumption. Comprising of nearly 7000 chemicals, cigarette smoke have both free radicals and oxidizing agents in both smoke tar and gas phase, both of which can cause oxidative stress in human health. Long time smoking causes decreased serum immunoglobulin level but increased level of auto– antibodies. During chronic oxidative stress resulting from cigarette smoking, cells secrete mucus and increased viscosity of mucus in airways makes it susceptible to bacterial infection. Furthermore, chronic exposure of lungs to tobacco smoke causes unfolded protein response, ER stress and altered ceramide metabolism. Apart from the above mentioned facts, Cigarette smoking can also cause senescence resulting in abnormal wound healing that exaggerates pathogenesis of COPD. Although there are several management therapies available for COPD management, but the permanent cellular damages due to smoking are irreparable and results in disease exaggeration and suffering.
Authors and Affiliations
Sudip Dey; Pokhraj Guha
Keywords
Related Articles
- EP ID EP702236
- DOI https://doi.org/10.52756/ijerr.2020.v23.002
- Views 105
- Downloads 0
Documentation and diversity analysis by DNA fingerprinting of the indigenous Mango (Mangifera indica L.) germplasm of West Bengal
Mango (Mangifera indica L.) has been reported to have extensive diversity due to alloploidy, outbreeding, continuous grafting and phenotypic differences arising from varied agro climatic conditions in different mango gro...
Assessment of Women's Online Shopping Behavior in India: Model Design and Analysis
The exponential increase in internet usage in India has driven the swift growth of e-commerce, with women playing a crucial role in this expanding digital economy. This research presents a thorough literature analysis an...
Occurrences of seven new records of goat fishes (family: Mullidae) from the coastal waters ofWest Bengal, India
Thirty eight fish specimens of family Mullidae were collected during the ornamental faunal survey around the West Bengal coast. All these specimens were identified into seven species which are addition to the faunal reso...
Study on the toxicity of neem (Azadirachta indica A. Juss) leaf extracts as phytopiscicide on three life stages of Mozambique tilapia (Oreochromis mossambicus Peters) with special reference to their ethological responses
Acute toxicity of leaf extracts of neem (Azadirachta indica A. Juss) on three different stages of fresh water weed fish Oreochromis mossambicus was investigated in the present study. The 24, 48, 72 and 96 h LC50 values f...
Effective medical leaf identification using hybridization of GMM-CNN
Medical plants play a vital role in curing many diseases. These plants, along with their leaves, have medicinal values. If these leaves are identified appropriately, they can be chosen directly to have more significant r...