A case control analysis to find association between PCO and endometrial carcinoma (EC)
Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 9
Abstract
Background: Endometrial cancer is one of the commonest cancers in women. Unopposed estrogen stimulation of the uterus is amongst one of the etiologies postulated for this condition. It is generally assumed that women with polycystic ovary syndrome are more likely to develop endometrial carcinoma. Aim: This study hypothesized comparing the ovarian morphology of women diagnosed with endometrial carcinoma and those with benign gynecological conditions. Materials and methods: The present study included a total 64 patients who had been diagnosed with endometrial carcinoma and with 42 age matched control. All biopsy samples were undergone routine histological process with Hematoxylin-Eosin stain to check morphological differentiation. Results: There was found no significant difference in the prevalence of PCOS (using this as a marker of PCOS in the absence of information on biochemistry) in the ovaries of patients diagnosed with endometrial cancer compared to women with benign gynaecology disease. Conclusion: Although our numbers were small, these results challenge the assumption that PCOS is a risk factor for endometrial cancer. Investigation of patient records revealed there was no significant difference in the demographic profile between subjects with endometrial carcinoma or benign gynecological conditions.
Authors and Affiliations
CH. Sheethal
Keywords
Related Articles
- EP ID EP495375
- DOI -
- Views 131
- Downloads 0
Lipid profile in assessing the severity of cirrhosis
Background: Cirrhosis is a common hepatological disorder seen in clinical practice. Liver plays an essential role in lipid metabolism, several stages of lipid synthesis and transportation. It is reasonable to expect an a...
A comparative study of inguinal hernia repair by Shouldice method vs other methods
Background: Hernia is one of the most common surgical conditions encountered in day to day practice. It is a common problem, more in industrial workers who are doing strenuous work over a long period of time. Any method...
Serial CT Scan following Traumatic Brain Injury: Its Significance and Analysis
Introduction: CT plays a key role in accurate diagnosis and important diagnostic tool in the management of traumatic brain injury. Materials and methods: Present study was under taken in the Department of Surgery Gandhi...
Surgical management in portal hypertension
Background: Portal hypertension commonly accompanies cirrhosis of liver and is a consequence of an increase in splanchnic blood flow secondary to vasodilatation and increased resistance to the passage of blood through th...
Study of incidence and risk factors of urinary tract infection in catheterized patients admitted at tertiary care hospital, Nizamabad, Telangana State, India
Background: Catheter-associated urinary tract infections (CAUTIs) are the most common hospital acquired infections and a leading cause of morbidity and mortality in hospitalized patients with various life threatening com...