A case control analysis to find association between PCO and endometrial carcinoma (EC)

Journal Title: International Archives of Integrated Medicine - Year 2016, Vol 3, Issue 9

Abstract

Background: Endometrial cancer is one of the commonest cancers in women. Unopposed estrogen stimulation of the uterus is amongst one of the etiologies postulated for this condition. It is generally assumed that women with polycystic ovary syndrome are more likely to develop endometrial carcinoma. Aim: This study hypothesized comparing the ovarian morphology of women diagnosed with endometrial carcinoma and those with benign gynecological conditions. Materials and methods: The present study included a total 64 patients who had been diagnosed with endometrial carcinoma and with 42 age matched control. All biopsy samples were undergone routine histological process with Hematoxylin-Eosin stain to check morphological differentiation. Results: There was found no significant difference in the prevalence of PCOS (using this as a marker of PCOS in the absence of information on biochemistry) in the ovaries of patients diagnosed with endometrial cancer compared to women with benign gynaecology disease. Conclusion: Although our numbers were small, these results challenge the assumption that PCOS is a risk factor for endometrial cancer. Investigation of patient records revealed there was no significant difference in the demographic profile between subjects with endometrial carcinoma or benign gynecological conditions.

Authors and Affiliations

CH. Sheethal

Keywords

Related Articles

Comparative study of serum ferritin level in simple and complex febrile seizures in Government Tirunelveli Medical College

Background: Febrile seizures are one of the common reasons for emergency room visits in pediatric population affecting up to one in twenty children in various parts of the world. Though febrile seizures are commonly beni...

Renal cell carcinoma - A spectrum of radiological findings

Background: Renal cell carcinomas (RCC) are primary malignant adenocarcinomas derived from the renal tubular epithelium and are the most common malignant renal tumor. They usually occur in 50-70-year-old patients. Aim: R...

Giant lipoma of breast: A rare case report

Lipomas are most common benign tumours derived from adipose tissue. Lipoma breast is somewhat difficult to diagnose clinically because of fatty consistency of breast. Lipoma breast measuring more than 10 cm in diameter o...

Effect of bupivacaine and bupivacaine-clonidine combination in supraclavicular brachial plexus block – A comparative study

Addition of clonidine to local anesthetics improves peripheral nerve blocks by reducing the onset time, improving the efficacy and extending postoperative analgesia. This study evaluated the effect of Bupivacaine clonidi...

Fibroadenolipoma of breast - A rare case report

Fibroadenolipoma is a solid, rare benign tumor. It is a circumscribed lesion composed of fat and other breast tissues which may be normal or which may show various changes. The reported incidence of breast hamartomas is...

Download PDF file
  • EP ID EP495375
  • DOI -
  • Views 129
  • Downloads 0

How To Cite

CH. Sheethal (2016). A case control analysis to find association between PCO and endometrial carcinoma (EC). International Archives of Integrated Medicine, 3(9), 93-97. https://europub.co.uk/articles/-A-495375