A case of bilateral Sertoli cell adenoma in androgen insensitivity syndrome

Journal Title: Ege Tıp Dergisi - Year 2017, Vol 56, Issue 3

Abstract

Androgen insensitivity syndrome, previously referred to as testicular feminization syndrome, is an X-linked recessive disorder that is characterized by a mutation in the q11-q12 region of the X chromosome, which results in a deformed androgen receptor gene. Patients with androgen insensitivity syndrome may develop testicular tumors, especially seminomas after puberty. A 35-year-old female patient presented with the complaint of primary amenorrhea and had masses of approximately 4 cm size palpated in the bilateral inguinal regions. The masses were excised and the histopathological examination was reported as bilateral Sertoli cell adenoma. Although the risk of bilateral gonadal tumor development is low in patients with androgen insensitivity syndrome, such malignancies should not be disregarded.

Authors and Affiliations

Zeynep Öztürk İnal, Nursadan Gergerlioğlu, İlknur Küçükosmanoğlu, Meryem İlkay Karanis

Keywords

Related Articles

Partial anomalous pulmonary venous return with intact atrial septum: A rare congenital anomaly

Partial anomalous pulmonary venous return with intact atrial septum anomaly is usually asymtomatic in pediatric population. Diagnose of this anomaly can be challenging with our routine eveluation methods like ECG, teleca...

Tracheal intubatı̇on wı̇thout muscle relaxants in chı̇ldren

Aim: Tracheal intubation without muscle relaxants is usually performed with alfentanil and propofol or sevoflurane. Alfentanil 5 to 40 μg/kg, propofol 2.0-4.0 mg/kg sevoflurane up to 1 MAC provide excellent or good intub...

Diz artroskopisi ve inguinal herni cerrahisinde ünilateral ve bilateral spinal anestezi uygulamalarında qtc değişikliklerinin karşılaştırılması

Amaç: Kardiyovasküler sistem üzerine etkileri ve düzeltilmiş QT değeri (QTc) değişiklikleri açısından ünilateral ve bilateral spinal anestezi yöntemlerinin hasta grupları üzerinde karşılaştırılması amaçlandı. Gereç ve Yö...

Complex regional pain syndrome type 1 in a child

Complex regional pain syndrome type 1 (CRPS 1), formerly known as reflex sympathetic dystrophy (RSD), is characterized by pain, sensory and vasomotor disturbances, trophic changes and impaired motor function. The pathoge...

The role of cardiac imaging modalities in risk stratification of patients with hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disorder. It is the most common reason of sudden cardiac death (SCD) in young athletes. Prevention of these deaths is of high concern among physicians. Patients with...

Download PDF file
  • EP ID EP336070
  • DOI 10.19161/etd.393585
  • Views 161
  • Downloads 0

How To Cite

Zeynep Öztürk İnal, Nursadan Gergerlioğlu, İlknur Küçükosmanoğlu, Meryem İlkay Karanis (2017). A case of bilateral Sertoli cell adenoma in androgen insensitivity syndrome. Ege Tıp Dergisi, 56(3), 154-156. https://europub.co.uk/articles/-A-336070