A case of primary gastric choriocarcinoma and a review of the Turkish literature:An extremely rare carcinoma of the stomach
Journal Title: Dicle Tıp Dergisi - Year 2012, Vol 39, Issue 1
Abstract
Primary choriocarcinoma of the stomach is an extremely rare and highly malignant tumor. A 60 years old man visited another hospital for the chief complaint of the stomachache and black stools. A large ulcero-vegetative tumor occupying the gastric body and antrum was seen in the upper gastrointestinal endoscopy. It was diagnosed as gastric adenocarcinoma by endoscopic biopsy. The patient admitted to our hospital for treatment. The patient was assessed as a gastric adenocarcinoma complicated with hemorrhage. In the exploration, it was observed that the mass arising from gastric body was invaded the transverse colon and pancreas. The lymphadenopaties in the celiac axis were conglomerated and had invaded the celiac vessels. A subtotal gastrectomy and an extended right hemicolectomy were performed for palliation. In pathological findings, typical characteristics of two cell pattern consisting of syncytiotrophoblasts and cytotrophoblasts were observed. The tumor consisted of only choriocarcinoma. For the definite diagnosis of choriocarcinoma, immunohistochemi- cal tests were performed. Beta-HCG and EMA staining were positive. The patient was invited for control because of gastric choriocarcinoma three weeks later surgery. His serum beta-HCG level was 458 mIU/mL (normal range, <0.5 mIU/mL). For the differantiation from the primary choriocarcinoma in the testis or mediastinum, testicular ultrasonography and chest CT were performed. Abnormal findings were not detected in the tests, so it was diagnosed as primary gastric choriocarcinoma. The patient refused chemotherapy. Three months later, he had inguinal lymphadenopaties and multiple metastases in lung. He died 5 months after surgery because of respiratory failure.
Authors and Affiliations
Cüneyt Kırkıl, Koray Karabulut, Erhan Aygen, Yavuz İlhan, Mesut Yur, İbrahim Özercan
Keywords
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