A CASE OF SYSTEMIC HYPEREOSINOPHILIA ASSOCIATED WITH DOXYCYCLINE USE
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 3
Abstract
Hypereosinophilic syndromes have been attributed to certain drugs in the literature, including minocycline. These syndromes may be restricted to a single organ or may involve multiple systems. We report the case of a 22-year-old woman with a history of atopy who developed peripheral hypereosinophilia after treatment with doxycycline for cellulitis, which was later found to be eosinophilic in nature. Doxycycline was discontinued on admission, but several days later she developed respiratory distress and bilateral infiltrates on chest radiograph. Bronchoalveolar lavage revealed 56% eosinophils consistent with eosinophilic pneumonia. To our knowledge, this is the first reported case of a hypereosinophilic syndrome following exposure to doxycycline.
Authors and Affiliations
Dr. Adan Mora Jr.
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