A case report of levetiracetam Ingestion and raise in Prothrombin time and International Normalized Ratio (INR)

Journal Title: Telangana Journal of Psychiatry - Year 2017, Vol 3, Issue 2

Abstract

We report a case of raised Prothrombin Time (PT) and International Normalized Ratio (INR) in a young male after ingestion of 3500 mgs of Levetiracetam as a suicidal attempt. No thrombocytopenia or raised liver enzyme disturbances were noticed. There were no previous published reports of such findings. Previous published reports of platelet related dysfunction and some reports of thrombocytopenia would be discussed in the light of our findings. Introduction: levetiracetam (LEV) is an antiepileptic drug approved for adjunctive use in partial seizures by United States food and drug administration (FDA) in 1999.The maximum recommended dose is 3000 mg daily. It is known to have mild side effect profile with headache, somnolence, dizziness, infection and asthenia1. However, hematological side effects are rare. We report a case of suicidal attempt with LEV and prolonged Prothrombin time which resolved over time.

Authors and Affiliations

Anand Bhogaraju, Sai Vittal, Anusha. K, Ravikanth. T

Keywords

Related Articles

Viktor Emil Frankl

Viktor Emil Frankl was an Austrian Neurologist and Psychiatrist He worked from the frame work of existential therapy During world war II he was under Nazi captivity it is this experience that shaped his work and developm...

Efficacy of Mindful- based Intervention on Behaviour Regulation Index of Executive Functions among Students with Inattention

Background: The objective of the present study is to explore the effectiveness of mindful-based practices on behaviour regulation index (BRI) of executive functions among students with inattention. Material and Method: T...

Stalwarts: Wilder Penfield

Wilder Penfeild, professor of neurology and neurosurgery at MC gill revolutionised our understanding of human brain .He was most famous for his experiments where he stimulated the brain of patients who had part of their...

Attitude towards illness and behavioral problems among HIV/AIDS orphaned children and other chronically ill children – A comparative study

Objective: To find out the attitude towards illness and behavioral problems among orphaned children suffering from HIV/AIDS and other chronically ill children – A comparative study. Materials and Methods: The current stu...

Effectiveness of emotional competence skills programme for adolescents: Results of a pilot study from India

Introduction: Emotional difficulties pose a greater threat to the overall well-being and quality of life of adolescents. Despite the need, a gap exists between research and implementation of school based promotive interv...

Download PDF file
  • EP ID EP302441
  • DOI 10.18231/2455-8559.2017.0028
  • Views 100
  • Downloads 0

How To Cite

Anand Bhogaraju, Sai Vittal, Anusha. K, Ravikanth. T (2017). A case report of levetiracetam Ingestion and raise in Prothrombin time and International Normalized Ratio (INR). Telangana Journal of Psychiatry, 3(2), 130-131. https://europub.co.uk/articles/-A-302441