A CASE STUDY OF BRAIN VOLUME REDUCTION IN MULTIPLE SCLEROSIS

Journal Title: Journal of IMAB - Annual Proceeding (Scientific Papers) - Year 2013, Vol 19, Issue 3

Abstract

The development of sophisticated magnetic resonance imaging techniques and software for medical imaging processing and analysis has led to a significant progress in multiple sclerosis research and clinical care. The measurement of brain volumes provides a quantitative representation of damage, thus facilitating the objective follow-up process. The parameters obtained, though not being used routinely in clinical practice, are more and more often applied in clinical studies. The amount of whole brain and regional atrophy, estimated from serial scans, is considered important not only for disease progression, but also for cognitive dysfunction which is common in multiple sclerosis. In this paper we describe a volumetric study of two magnetic resonance scans of a patient with relapsing-remitting multiple sclerosis, performed 16 months one after the other, and analyzed using FSL SIENA software. Analysis demonstrated brain volume reduction of 1.7% between the two scans. We discuss the advantages of the method and its possible clinical applications.

Authors and Affiliations

Ivan Dimitrov, Ara Kaprelyan, Borislav Ivanov

Keywords

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  • EP ID EP151818
  • DOI 10.5272/jimab.2013193.438
  • Views 111
  • Downloads 0

How To Cite

Ivan Dimitrov, Ara Kaprelyan, Borislav Ivanov (2013). A CASE STUDY OF BRAIN VOLUME REDUCTION IN MULTIPLE SCLEROSIS. Journal of IMAB - Annual Proceeding (Scientific Papers), 19(3), 438-441. https://europub.co.uk/articles/-A-151818