A Cerebellar High-Grade Neuroepithelial Tumour with BCOR Alteration in a five-year-old Child: A case report

Journal Title: Sultan Qaboos University Medical Journal - Year 2019, Vol 19, Issue 2

Abstract

New groups of high-grade neuroepithelial tumours (HGNET) have emerged from the reclassification of central nervous system (CNS) embryonal tumours that have recognised CNS HGNET with BCOR alteration (CNS HGNET-BCOR). We report a two-year, nine-month-old Omani boy who presented to the Royal Hospital, Muscat, Oman, in 2015 with subacute head tilting and neck pain. A well-defined cerebellar lesion was found and he was treated with standard chemoradiotherapy. After a relapse at the age of five years, molecular testing revealed a BCOR alteration. He was treated with further surgery and high-dose chemotherapy; unfortunately, he relapsed and died three years after he was diagnosed.

Authors and Affiliations

Abeer Al-Battashi, Zahra Al Hajri, Arie Perry, Hunaina Al-Kindi, Ibrahim Al-Ghaithi

Keywords

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  • EP ID EP49975
  • DOI http://dx.doi.org/10.18295/squmj.2019.19.02.012
  • Views 330
  • Downloads 0

How To Cite

Abeer Al-Battashi, Zahra Al Hajri, Arie Perry, Hunaina Al-Kindi, Ibrahim Al-Ghaithi (2019). A Cerebellar High-Grade Neuroepithelial Tumour with BCOR Alteration in a five-year-old Child: A case report. Sultan Qaboos University Medical Journal, 19(2), -. https://europub.co.uk/articles/-A-49975