A Challenge between Central Nervous System Infection and Lead Toxicity: Opioid Case Reports from Iran

Journal Title: Iranian Journal of Medical Sciences - Year 2019, Vol 44, Issue 2

Abstract

Although lead pollution has long been known as a cause of poisoning, it has remained a challenge to reliably diagnose it due to its common symptoms in various diseases. In this article, we report two cases of acute loss of consciousness due to the ingestion of opium-contaminated with lead. The reported cases share patterns of symptoms similar to meningitis and encephalitis which are usual etiology for the loss of consciousness. Lead poisoning is not a usual etiology for loss of consciousness and is considered in cases of occupational or environmental exposure. These reported cases showed a pattern similar to meningitis and encephalitis, but due to the unusual manifestations during their admission and coexistence with gastrointestinal symptoms, we were led to consider poisoning as the cause of consciousness loss. Lead poisoning often goes unrecognized due to a low index of suspicion, but it may turn out to be fatal. Therefore, it should be considered in the differential diagnosis of any neurobehavioral deficits in substance abusers.

Authors and Affiliations

Minoosh Shabani, Maryam Nasiri, Zohreh Aminzadeh, Hossein Hassanian Moghaddam

Keywords

Related Articles

Adherence to Hypoglycemic Medication among Insulin-Treated Patients with Type 2 Diabetes

Type-2 diabetes is a progressive metabolic disease requiring ongoing medical care. Despite different therapeutic regimens for diabetes, only a few patients achieve the glycemic target,1 which might be the result of poor...

Radioprotective Efficacy of Lutein in Ameliorating Electron Beam Radiation-induced Oxidative Injury in Swiss Albino Mice

Background: Lutein, a carotenoid compound, has previously been studied for its antioxidant and medicinal properties as well as the moderate protection it confers against gamma radiation. This study aimed at evaluating th...

Correlation between Ultrafiltration Coefficient and Effective Lymphatic Absorption Rate in Continuous Ambulatory Peritoneal Dialysis Patients: A Possible Paradigm Shift

Background: The relative contribution of transcapillary water movement and lymphatic reabsorption in peritoneal dialysis (PD) is a critical issue, particularly in patients with ultrafiltration failure (UFF). Based on rou...

NDRG2 Regulates the Expression of Genes Involved in Epithelial Mesenchymal Transition of Prostate Cancer Cells

Background: Metastasis is the main cause of prostate cancer (PCa) death. The inhibitory effect of N-myc downstream-regulated gene 2 (NDRG2) on the invasiveness properties of PCa cells has been demonstrated previously. Ho...

The Most Common Allergenic Tree Pollen Grains in the Middle East: A Narrative Review

Allergy is becoming a major disease burden globally. Pollens are considered as the main component of aeroallergens that lead to rhinitis and asthma. Due to the lack of a comprehensive investigation on most allergic polle...

Download PDF file
  • EP ID EP478444
  • DOI -
  • Views 73
  • Downloads 0

How To Cite

Minoosh Shabani, Maryam Nasiri, Zohreh Aminzadeh, Hossein Hassanian Moghaddam (2019). A Challenge between Central Nervous System Infection and Lead Toxicity: Opioid Case Reports from Iran. Iranian Journal of Medical Sciences, 44(2), 168-171. https://europub.co.uk/articles/-A-478444