A CLINICAL, BACTERIOLOGICAL AND LABORATORIES PROFILE OF NEONATAL SEPTICAEMIA IN A TERTIARY CARE CENTRE OF EASTERN NEPAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 1
Abstract
BACKGROUND The most common neonatal morbidity and mortality in underdeveloped countries is neonatal sepsis. The vague clinical sign and symptoms need high degree of suspicion for the early diagnosis and treatment, while the continuously changing patterns of causative microbial flora and their sensitivity pattern cause problem in effective management of these cases. MATERIALS AND METHODS This retrospective descriptive study was conducted by studying the case reports of 325 newborns, which were (both inborn and outborn) admitted to BPKIHS Paediatric Ward, Nursery, NICU via Emergency over a period of one year from January 2012 to December 2012 with features suggestive of sepsis. RESULTS The total number of patients enrolled in this study was 325. Among them, 213 (65.5%) were male and 112 (34.5%) were female child. Male-to-female ratio was almost 2: 1. Early onset sepsis was found in 56.6% newborns, while 43.4% had late onset sepsis. Most of the newborns were presented with the complaints of fever (46.8%) followed by refusal of feed (39.7%) and respiratory distress. Blood culture from 13.2% newborns showed growth of pathologic organism. CONCLUSION Male sex has more tendency to develop neonatal sepsis than female. The risk of developing sepsis in male child is almost twice that of female child, which was statistically significant. The various risk factors are leaking, low birth weight, size corresponding to gestational age and prematurity. Fever, not sucking well, resp. distress, jaundice, lethargy, vomiting and seizure were the main chief complaints. Blood culture positivity rate was 13.2% with predominance of gram-positive organisms.
Authors and Affiliations
Pramendra Prasad Gupta, Sanjay Gupta, Rupak Bhandari, Shital Gupta, Lokraj shah
Keywords
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- EP ID EP283329
- DOI 10.14260/jemds/2018/9
- Views 87
- Downloads 0
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