A Clinical Study of Leptospirosis and Its Complications
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 12
Abstract
OBJETIVES: to review clinical features and related complications of leptospirosis in view of upsurge of leptospirosis in urban population. DESIGN:retrospective observational study SETTING: Mahatma Gandhi Mission Institute of Health Sciences, Navi Mumbai. PARTICIPANTS: Patients aged 60 years and above attending both in-patient and out-patient department with positive Leptospirosis IgM. METHODOLOGY: We conducted a systematic review of 35 patients attending both inpatient and outpatient department with positive Leptospirosis IgM. Detailed history of each patient was taken including laboratory investigations and physical examination. Patients in acute phase presented with symptoms like fever with chills, headache, vomiting, myalgia, breathlessness, icterus, cough and decreased urine output. Clinical and epidemiologic data was collected for each patient. Laboratory tests included complete blood count, liver function test, renal function test, urine routine and microscopy and leptospiraIgG, IgM. RESULTS: The 32 cases presented with following gender distribution: male (n=21) and female (n=11). Maximum cases were seen in Monsoon season. The main presenting complaints were fever and chills with occurred in 100% patients followed by headache and myalgia (93%), vomiting (87.5%) and oliguria (68.75%). Mortality increased with increase in number of complications. The most common complication was hepatic failure followed by renal failure. CONCLUSION: Leptospirosis remains one of the common febrile illness with myalgia and associated hepatorenal involvement needing prompt and early treatment for satisfactory outcome. Due to wide spectrum of clinical signs and symptoms, a high degree of clinical suspicion is necessary for timely diagnosis. People in endemic areas should be educated about the disease specially the signs and symptoms and advise to come to the hospital as early as possible for treatment which will prevent multi-organ failure and subsequent mortality.
Authors and Affiliations
Dr. Sayali Damle, Dr. Shwet Sabnis, Dr. T. K. Biswas
Keywords
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- EP ID EP423866
- DOI 10.9790/0853-1712073639.
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