A Clinical Study on Cardiac Autonomic Neuropathy (CAN) in Diabetes Mellitus
Journal Title: PARIPEX-Indian Journal of Research - Year 2016, Vol 5, Issue 11
Abstract
BACKGROUND Cardiovascular diseases are a common cause of morbidity and mortality in diabetic patients. Cardiac autonomic neuropathy , a clinically important type of diabetic autonomic neuropathy can be a significant cause of mortality in diabetic patients. AIMS AND OBJECTIVES a) To study the prevalence and risk factors for CAN in Type 1 and Type 2 DM. b) To study the sensitivity and specificity of corrected QT interval (QTc) in the ECG in diagnosis of CAN in DM. MATERIALS AND METHODS This is a cross-sectional study done among patients attending Diabetic clinic under the Department of General Medicine, Government Medical College Calicut. Tests were done to look for cardiac autonomic neuropathy and assess the prevalence and risk factors. The data was obtained after informed consent and analysed by EPI INFO (Ver 3.4.1) RESULTS The prevalence of CAN among the patients with DM in our study was 73%. An association of prevalence of CAN with increase in duration of the DM was found to be statistically significant. CONCLUSIONS CAN is a common complication of both type 1 & type 2 DM. Longer duration of DM and coexistent peripheral neuropathy and prolongation of QTc interval in ECG was associated with high prevalence of CAN in type 1 DM. Higher age, longer duration of DM and coexistent peripheral neuropathy are associated with higher prevalence of CAN in type 2 DM.
Authors and Affiliations
Anish Philip, K. G. Sajeeth Kumar
Keywords
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