A Clinical Study on Primary Lymphoma of the Thyroid in a Tertiary Hospital
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 8
Abstract
Background: The incidence of primary thyroid lymphoma is uncommon and accounts for <5% of all thyroid malignancies. Diagnosis by fine needle aspiration cytology (FNAC) is difficult due to its rarity, and therefore patients may undergo thyroidectomy unnecessarily. Aim of the Study: The aim of the study was to study the review the incidence of primary thyroid malignancies in a tertiary hospital and study the diagnostic as well therapeutic methods available. Materials and Methods: A total of 37 patients with primary lymphoma of thyroid over a period of 13 years managed were reviewed retrospectively for their clinical presentation, FNAC reports and modes of management. Observations and Results: Among 37 patients 26 (70.27%) were women and 11 (29.72%) were male patients. The previous history of thyroid disease was seen in 13 (35.13%) patients. The most common clinical presentation was mass in the neck in 31 (83.78%), dysphagia in 21 (56.75%), dyspnea in 18 (48.64%), and hoarseness of voice in 14 (37.83%). All the patients underwent FNAC. Primary diagnosis of primary thyroid lymphoma was made by FNAC in 12 (32.43%) of the 37 patients. Primary thyroiditis was reported in 4 (10.81%), follicular thyroid carcinoma in 7 (18.91%). In 14 patients (37.83%) FNAC was inconclusive and required hardcore biopsy in 6 (16.215), and 8 (21.62%) required incisional biopsy. Two patients required emergency debulking for airway obstruction. Overall among the 37 patients B-cell Non-Hodgkin’s Lymphoma (NHL) was observed in 31 (83.78%) and T-cell NHL in 6 (16.21%) patients. Conclusions: In rapidly growing thyroid goiters the diagnosis of primary thyroid lymphoma should be considered. FNAC is limited in diagnosing thyroid lymphoma but useful in the initial workup of thyroid goiters. However, surgical intervention to take biopsy is required to establish the diagnosis and relieve critical airway compression. A combination of chemotherapy and irradiation is the mainstay of management.
Authors and Affiliations
P G Ananda Kumar
Keywords
Related Articles
- EP ID EP474446
- DOI -
- Views 121
- Downloads 0
A Clinical and Epidemiological Analysis of First-time Febrile Seizures in Children
Background: Febrile seizures (FSs) are the most common neurological disorder observed in the pediatric age group. In pediatric practice, seizures account for 1% of all emergency visits. They are usually defined as seizur...
Evaluation of Chest Pain in Premenopausal Indian Women
Introduction: Chest pain is a major source of concern for patients and physicians alike as it may harbinger acute life-threatening cardiac events, yet many patients who describe chest pain typical of significant cardiac...
Comparison of the Efficacy of Tamsulosin and Placebo in the Management of Acute Urinary Retention Secondary to Benign Prostatic Hyperplasia Undergoing Trial without Catheter until Definitive Therapy
Introduction: Acute urinary retention (AUR) is one of the most significant, uncomfortable and inconvenient events in the natural history of benign prostatic hyperplasia (BPH). The immediate treatment is bladder decompres...
Study of Lab Parameters Predicting Post-discharge Mortality after Admission for Community-acquired Pneumonia: A Prospective Tertiary Hospital Care Based Study
Introduction: There are considerable morbidity and mortality following discharge of patients admitted as community-acquired pneumonia (CAP). There is very scarce data about follow-up of these patients after they are disc...
Metabolic Syndrome in Female Patients with Ischaemic Heart Disease: A prospective study
Introduction: Metabolic syndrome is a cluster of clinical characteristics that is associated with enhanced coronary risk. Materials and Methods: A total of 62 female patients with IHD were observed. These females were ha...