A CLINICAL STUDY TO COMPARE THE EFFICACY OF PAROXETINE VERSUS ASHWAGANDHA IN PATIENTS SUFFERING FROM GENERALIZED ANXIETY DISORDER.
Journal Title: IJSR-International Journal Of Scientific Research - Year 2017, Vol 6, Issue 3
Abstract
Anxiety disorders have a lifetime prevalence which exceeds 15% in the general population and particularly Generalized Anxiety Disorder (GAD) (lifetime prevalence of 5.1%) accounts for second most frequent psychiatric disorder in the primary care setting. METHODOLOGY e present 12 weeks' study was a prospective, randomized clinical study in 60 subjects. e aim of the study is to compare the efficacy between two drugs using HAM-A, HADS, CGI scales. Results: In Paroxetine group there was only very little clinical difference in HAM-A and HADS reduction than Ashwagandha group however the difference did not reach statistical significance. Similarly, reduction in CGI scores did not reach statistical significance. Conclusion: Ashwagandha (Withania Somnifera) when compared was as much efficacious as Paroxetine but had better side effect profile hence could be given in patients not tolerating the side effect of Selective serotonin reuptake inhibitors (SSRIs) or can be given in mild to moderate anxiety as an initial drug.
Authors and Affiliations
Sachchidanand Tewari, Mohit Trivedi
Keywords
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