A CLINICAL STUDY TO EVALUATE THE EFFICACY OF SAINDHAVADI TAILA MATRA VASTI IN THE MANAGEMENT OF AMAVATA W.S.R. RHEUMATOID ARTHRITIS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2017, Vol 10, Issue 12
Abstract
  Objective: The objective of the study is to find the efficacy of Saindhavadi Taila Matra Vasti in the management of Amavata (rheumatoid arthritis [RA]).Methods: For the present clinical study 15 patients of Amavata (RA) were registered from the Outpatient Department, PG Department of Kayachikitsa, Rishikul Campus, Haridwar. Saindhavadi Taila Matra Vasti was given 60 ml once daily for 8 days, followed by an interval of 7 days. Again Vasti was given once daily for 8 days followed by gap of 7 days. Same cycle was repeated next month. Assessment of the patients was done on the basis of subjective, objective, and functional parameters at the interval of 15 days.Results: Statistically significant result was found in subjective parameters such as pain intensity, Sandhishotha, Gaurav, Apaka (p<0.01 in each), Jwara, Aruchi, and Utsahahani (p<0.05 in each). Statistically non-significant result was found in all the functional parameters (p>0.05), that is, in grip strength, foot pressure, and goniometry. In biochemical parameters, statistically significant result was found in erythrocyte sedimentation rate only (p<0.05). Although non-significant result was found in other biochemical parameters such as hemoglobin, RA factor, and C-reactive protein (CRP) concentration, the mean scores of RA factor and CRP were reduced from 48.7 IU/ml and 10.4 mg/L before treatment to 25.8 IU/ml, 8.2 mg/L after treatment, respectively.Conclusion: In the clinical study, patients got symptomatic relief in many of the complaints but no significant result was found in functional parameters and most of the biochemical parameters. Thus, it can be concluded that Saindhavadi Taila Matra Vasti alone is effective in mild-to-moderate cases of Amavata (RA) and in severe cases it can be used along with oral Ayurvedic formulations for better results.
Authors and Affiliations
Archana Negi, Punita Pandey, Bhupinder Singh
COMPARATIVE PHYTOCHEMICAL SCREENING AND ANTIOXIDANT PROPERTIES OF IN VITRO AND IN VIVO PROPAGATED ORTHOSIPHON STAMINEUS BENTH (LAMIACEAE).
Objective: Present study aims in in vitro propagation of the valuable medicinal plant, Orthosiphon stamineus in various concentrations of plant growth regulators and to compare the antioxidant activity and phytochemical...
ANTIBACTERIAL ACTIVITIES OF ANREDERA CORDIFOLIA (TEN.) V. STEENIS LEAVES EXTRACTS AND FRACTIONS
  Objective: This study aims to determine antibacterial activity of Anredera cordifolia leaves extracts and fractions.Methods: Crude drug was extracted using two methods. First method was extraction by reflux using eth...
WHEN THE “RIGHT WAS WRONGâ€: A CASE OF “MISSED NEGLIGENCEâ€
 We report a case where the operation site was marked wrongly on the right side of the scalp. It was the timely intervention of a member of the surgicalteam that the possible mishap in the form of a negligent operation...
MOLECULAR DOCKING STUDIES ON EGF – 5 FLUOROURACIL
Cancer can be described as the uncontrolled growth of abnormal cells. 5 Fluorouracil is an anticancer drug which has it effects on colon cancer, brain tumor, breast cancer, head & neck cancer. The aim of the present...
A RANDOMIZED CLINICAL ENDPOINT STUDY TO EVALUATE THE SAFETY AND EFFICACY OF CLEARLIV TABLETS IN PATIENTS WITH ALCOHOLIC LIVER DISEASE
Objective: The objective of this study was to evaluate and compare the hepatoprotective effect of clearliv tablets with silymarin in patients with alcoholic liver disease.Methods: This was a prospective, randomized, mult...