A CLINICO-AETIOPATHOLOGICAL STUDY OF PALMOPLANTAR KERATODERMA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 13
Abstract
BACKGROUND Palmoplantar keratodermas (PPKs) are a diverse entity of disorders that are characterised by abnormal thickening of the skin on the palms and soles. Over 50 types have been described and many of the inheritable types have been well documented in a review article by Itin and Fistarol. There is a considerable overlap and variation in clinical and histopathological feature of these conditions. Thus, a clinicopathological correlation is required for appropriate diagnosis. This would help in a better management of patients. Aims and Objectives- To study the various aetiological factors causing palmoplantar keratoderma (PPK), to study the histopathological features of various types of palmoplantar keratoderma (PPK). MATERIALS AND METHODS Hundred (100) consecutive patients of palmoplantar keratoderma fulfilling the inclusion criteria, attending the outpatient Department of Dermatology, STD and leprosy, at the tertiary care centre of our medical college. After detailed history complete general, systemic and cutaneous examination was done with reference to lesions on the other parts of the body, any other dermatoses or systemic diseases. Skin biopsy was done in all the patients. Routine investigations like complete blood picture, complete urine examination, random blood sugar, serum creatinine and other tests like thyroid profile, VDRL, HIV 1 and 2 antibodies, potassium hydroxide mount of skin scrapings and PAS staining of biopsy section were done wherever necessary. Settings and Design- An observational study. RESULTS Patient’s age ranged from 8 to 70 years (mean age being 31). Common age group was 11 - 20 years (24.00 %) followed by 21 - 30 years (22.00%), 31 - 40 years (20%), 41 - 50 years (14%), < 10 years (8%), 51 - 60 years (6%) and 61 - 70 years (6%), not seen between 71 - 80 years. Out of the total 100 patients studied, 44.00% were male and 56.00% were female patients. Male-to-female ratio was 0.78 showing female preponderance. Occurrence of PPK was seen among manual labourers (28.00%), students (20.00%), housewives (16.00%) and agricultural workers (10.00%). Involvement of palms and soles was seen in 48.0% followed by soles 28.0% and palms in 24%. Clinically, 34% patients were diagnosed by psoriasis, 26% eczema, 10% HPPK, 8% pityriasis rubra pilaris, 8% with atopic dermatitis and 2% patients with drug-induced keratoderma and 10% patients with hereditary palmoplantar keratoderma. Histopathologically, out of 34 clinically diagnosed psoriasis 24 showed typical changes, while 18 out of 26 patients showed changes of eczema. All 6 clinically diagnosed patients showed typical changes of lichen planus. All 8 clinically diagnosed patients showed typical changes of Pityriasis rubra pilaris. CONCLUSION The present study documented higher prevalence of palmoplantar keratoderma in the patients of age group 11 - 20 years with female preponderance. Psoriasis was more common among males and eczemas was more common in females.
Authors and Affiliations
Fatima Razvi, Nayeem Sadath Haneef, Sriteja V, Chudi Kavya Reddy, Fatima Ummul Hasnath, Ramesh Bang
Keywords
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- EP ID EP412230
- DOI 10.14260/jemds/2018/367
- Views 70
- Downloads 0
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