A Clinico-Pathological Study of Cutaneous Lupus Erythematosus
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 11
Abstract
Background: Lupus erythematosus (LE) is a heterogenous autoimmune disease marked by diverse patterns of autoantibody production that can affect one or more vital internal organs as well as skin. Skin is the second most commonly affected organ in patients with lupus erythematosus. Skin involvement may occur alone or as a part of serious systemic disease Materials and Methods: A clinical non-interventional descriptive study was conducted in a tertiary care centre over a period of 1 year. Aim: 1. To study the clinical patterns and histopathology of these clinical patterns of cutaneous lupus erythematosus. 2. To study the risk factors, all the required data were collected by clinical examination of patients. Results: Thirty patients with clinical features of cutaneous lupus erythematosus were studied and the following observations were made. Patients with cutaneous LE ranged in age from 20-62 years. the male to female ratio was 1:5. Seventy percent of the patients were unemployed. Scaly rash was the most frequent complaint. Seventeen (56.7%) patients with cutaneous LE had systemic complaints. Majority of patients (26) had short duration illness of less than 1 year. Seventeen (56.7%) patients attributed sunlight as an exacerbating factor Chronic CLE (CCLE) was the most common form of cutaneous LE observed in this study. LE nonspecific lesions were observed in 53.3% patients with cutaneous LE. Among the 25 histopathologically diagnosed cases of classic CCLE, hyperkeratosis, follicular plugging and atrophy were present in 76%, keratotic plugging in 32%, acanthosis in 24% and hypergranulosis with parakeratosis in 4%.
Authors and Affiliations
Dr Rony Mathew
Keywords
Related Articles
- EP ID EP525443
- DOI -
- Views 52
- Downloads 0
Role of Flexible Video Bronchoscopy in Diagnosis of Pulmonary Lesions
Flexible video bronchoscopy is very useful & safe procedure for diagnosis of respiratory diseases. It can be performed under local anesthesia in various clinics/hospitals settings providing maximal visualization of trach...
Effects of Snakebite in India
Objective: To study the respondent’s clinical profile of snake envenomation in a tertiary referral of Pondicherry in India. Material and Methods: Retrospective case note treatment analysis of all cases (75 cases) of snak...
Clinical Spectrum and Surgical outcome of Follicular Variant of Papillary Carcinoma of Lingual Thyroid with Nodal Metastasis in Neck and Absent Orthotopic Thyroid Gland
Lingual thyroid is relatively uncommon developmental defect of thyroid gland embryogenesis. We report a case of 48 year-old female patient who presented to us with swellings in both side of neck since 2 years. She was di...
A Comparative Prospective Study of Platelet Rich Plasma vs Corticosteroid Injection in Lateral Epicondylitis
Introduction: Lateral epicondylitis, is seen to affect 1% to 3% of the general population in the 3rd and 4th decade of life and is one of the most common causes for elbow pain. Various treatment modalities have been used...
Epidemiological Analysis and Clinical Characteristics of Traumatic Brain Injury in Southern Rajasthan: A Hospital Based Study
Background: Traumatic Brain Injury, also known as intracranial injury is a significant public health problem and also a major leading cause of disability and mortality in all regions of the globe despite advancement in p...