A Clinicopathologic Study of Melanocytic Neoplasms
Journal Title: Saudi Journal of Pathology and Microbiology - Year 2017, Vol 2, Issue 8
Abstract
Abstract:This study reports baseline information about melanocytic neoplasms in TUTH. The objective was to study the histological spectrum of melanocytic nevi and melanoma, and to make a clinicohistopathological correlation. 50 consecutive cases of melanocytic neoplasms were studied from December 2010 to December 2011.Of the 50 cases, 12 (24%) were malignant melanoma and 38(76%) were melanocytic nevi. Cutaneous melanocytic nevi was the commonest, 30/38, (79%) followed by 8/38 (21%) conjunctival nevi. Head and neck was the commonest site (25/38) and the mean age at presentation was 32.66 +16.19 years, the female to male ratio being 5.3:1.In melanoma, 4 (33%) were extracutaneous, of the cutaneous, 2 (17%) were acrallentiginous, and 6 (50%) were nodular. Mean age was 50 + 16.99 years with an equal female to male ratio. Commonest site was extremities (6/8) in cutaneous and choroid in extracutaneous (2/4) lesions. Concordance between clinical and histopathological diagnosis were found in 30/50 (60%) cases. Melanocytic nevi are quite common in females, melanoma is rare, affecting men and women equally. In our context melanoma likely represents a sporadic disorder. Difference from the western societies is the common occurrence of nodular melanoma here and the topographical distribution. Keywords:Cutaneous and Extracutaneous, Clinicopathologic, Melanocytic Neoplasms
Authors and Affiliations
Niharika Shah, R. C. Adhikari, Shovana Karki, Deebya Raj Mishra, Nidhi Shah
Keywords
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