A CLINICOPATHOLOGICAL STUDY OF LACRIMAL FOSSA LESIONS AT A TERTIARY CARE CENTRE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 91
Abstract
BACKGROUND Lesions of the lacrimal fossa and gland constitute about 5% - 13% of all orbital masses confirmed by biopsy. The diagnosis, the histopathological correlation and treatment of lacrimal fossa lesions are important to ophthalmologists. The aim of this study is to analyse retrospectively 31 cases of lacrimal fossa lesions diagnosed over a 10-year period. MATERIALS AND METHODS The clinical features and the histopathological features of 31 cases diagnosed as lacrimal fossa lesions between 2004 September and 2014 August were retrospectively analysed from case records in a tertiary care centre at Department of Ophthalmology, KR Hospital, MMC and RI, Mysore. RESULTS The present study includes 31 cases of lacrimal fossa lesions over a period of 10 years. The age of patients spanned from 5 - 74 years. Among the total 31 cases, 15 (48.39%) were male and 16 (51.61%) were female. The most frequent primary epithelial tumour in benign was pleomorphic adenoma (19.35%) and malignant epithelial tumours were adenocystic carcinoma (3.23%), mucoepidermoid carcinoma (3.23%) and carcinoma ex pleomorphic adenoma (3.23%). Among the patients reviewed 38.71% had inflammatory lacrimal gland lesions, 48.39% epithelial lesions and 12.9% lymphoproliferative lesions. The study included 90.32% benign lesions and 9.68% malignant lesions. According to the pathological origin of the lesions, they may be classified into 51.61% non-epithelial lesions and 48.39% epithelial lesions, 9.68% malignant epithelial tumours, 19.35% benign epithelial tumours, 6.45% dacryops and dermoid 12.9%. CONCLUSION Lacrimal fossa lesions show a wide pathological range. Inflammatory lesions are most frequent, followed by epithelial lesions. Analysis of clinical and radiological criteria is helpful in the differential diagnosis of lacrimal gland lesions.
Authors and Affiliations
Hemalatha Krishnamurthy, Manjula Devi N, Venkategowda H. T, Archana S, Amulya Padmini H. M, Padmini S, Aayesha Fatima, Shwetha G. R
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