A Comparative clinical study of Ksharsutra ligation and Lateral Internal Sphincterotomy in the management of Parikartika (Chronic Fissure-in-Ano)
Journal Title: International Journal of Pharmaceutical & Biological Archive - Year 2017, Vol 8, Issue 6
Abstract
Background: Parikartika which resembles fissure-in-ano described as a complication of various diseases in Ayurvedic texts such as Vatika jwara, Vatika pakwa atisara, Sahaja arsha, Kaphaja arsha, Arsha purvarupa, Udavarta, complication of pregnancy (Garbhini), unlawful administration of purgative or enema (Basti), complication of Vamana and Virechana. As Ksharsutra , proven successful treatment modality for fistula-in-ano and piles to try its efficacy in chronic fissure-in-ano. Aim: To compare Apamarga Ksharsutra ligation and Lateral Internal Sphincterotomy (LIS) in the management of Parikartika (Chronic fissure-in-ano). Materials and Methods: Total 30 patients of Parikartika were selected and randomly divided in to two Groups (15 in each group). In group-A, Ksharsutra ligation with maximum possible anal dilatation was carried out while in group-B Lateral Internal Sphincterotomy with excision of skin tag was carried out under local anesthesia. Relief in symptoms and post operative complications in subjects were assessed for 4 weeks and follow up period was 1 month. Results: In both groups, significant results were found individually but difference was statistically insignificant. Duration required for relief in post- operative pain, bleeding, swelling and wound healing was found more in group-A (Ksharsutra) than group-B (LIS). Conclusion: Lateral Internal Sphincterotomy produced better results in compare to Ksharsutra ligation in the management of Parikartika (Chronic Fissure-in-Ano).
Pharmacognostical and antioxidant activity investigations on Vernonia anthelmintica Wild fruits
Vernonia anthelmintica Willd. (Asteraceae) is an annual herb used conventionally for the management of diabetes, fever, wound, malaria, cancer, acne and stomach disorder. As the plant is of ethno-pharmacological relevanc...
Screening of antimicrobial and antioxidant activities of endophytic actinomycetes isolated from Rhizophora mucronata and Sonneratia caseolaris
The aim of the present study was to evaluate the antimicrobial and antioxidant activity of crude extract or secondary metabolites of Endophytic actinomycetes species isolated from two mangrove plants collected from Corta...
Molecular Characterization, Phytochemical Analysis, Antioxidant and Anticancer Potentials of Wrightia tinctoria
In worldwide the use of the plant materials to prevent and treat infectious diseases successfully over the years has attracted the attention of scientists. Plant based anticancer/antioxidant compounds can serve the purpo...
Role of Cytokines in Pathogenesis of Rheumatoid Arthritis
Rheumatoid arthritis has multi factorial pathogenesis synovial hyperplasia and joint deformation is a striking characteristic of RA patients. The synovium thickens, and the joint becomes swollen and painful. In arthritis...
Botanical Cosmeceuticals for skin care
Currently a new term in the cosmetic industry is 'Cosmeceuticals', which is the fastest growing segment of the natural personal care trade. They are the next generation of skin care. 'Cosmeceuticals' are the advances mad...