A comparative effectiveness of activated platelet-rich plasma versus autologous whole blood in the management of lateral epicondylitis: A randomized clinical trial of functional outcome
Journal Title: International Journal of Orthopaedics Sciences - Year 2018, Vol 4, Issue 1
Abstract
Background: Lateral epicondylitis (tennis elbow), a familiar term used to describe myriad of symptoms around the lateral aspect of elbow mainly due to intra-tendinous degeneration assosciated with ageing, repetitive movement and vascular compromise. Activated platelet-rich plama (PRP) and Autologous whole blood (AWB) injections represent new therapeutic options for chronic tendinopathies including tennis elbow. But from the literature, no firm conclusions can be drawn about the effectiveness of PRP versus AWB or the superiority of one method over the other. Our aim of study was to compare the effectiveness and functional outcome of both modalities. Methods: 50 patients with chronic lateral epicondylitis (>3 months) with restricted ROM were included in this study and randomized into 2 groups. Group 1 was treated with a single injection of 2 mL of autologous PRP (4.8 times of plasma) with 1ml of calcium chloride as activator and group 2 with 2 mL of AWB injection followed by elbow-strap, stretching and strengthening exercises for both groups. Pain and functional outcomes were assessed using visual analogue scale (VAS) and NIRSCHL staging (NS) at 0, 4, 8 weeks, 6 months and 12 months. Results: Pain variables including VAS and Nirschl scores improved significantly in both groups at short and intermediate duration but on long term follow up intervals PRP showed better improvement between groups regarding pain severity, functional improvement and recurrence rates. Conclusion: Both PRP and AWB injections are effective to treat chronic lateral epicondylitis but for longer duration the efficacy persisted with PRP seems to be superior than AWB.
Authors and Affiliations
Kanwarjit Singh Sandhu, BS Brar, Dr. Amandeep Singh Bakshi, Dr. N Bobby, Dr. Kanchan Bhardwaj, Dr. Sanjeev Sreen, Dr. Pardeep Kumar
Keywords
Related Articles
- EP ID EP483366
- DOI 10.22271/ortho.2018.v4.i1e.43
- Views 95
- Downloads 0
Role of plain shoe insoles in the management of knee osteoarthritis
Knee osteoarthritis, which most commonly affects the medial compartment, is a chronic joint disorder that imposes a major healthcare burden. It imposes a significant economic burden and is associated with considerable pa...
Assessment of results of different modalities of treatments in fractures of Tibial plateau
Introduction: The knee joint is complex joint and is the commonly injured joint now a day because of increased vehicular trauma and sports related injuries. Being superficial joint and more exposed to external forces, th...
Tibial diaphyseal fractures managed surgically by interlocking intramedullary nailing: A prospective study
The tibia is by far the commonly fractured long bone in the human body, as it has got a poor soft tissue coverage and its medial surface is almost completely subcutaneous. Tibial diaphyseal fractures are treated surgical...
Posterior cruciate ligament avulsion from the Tibia: Fixation by a posterior approach
The authors present their experience with a posterior approach for fixation of posterior Cruciate ligament avulsion from the tibia. Avulsion usually occurs at the tibial insertion. The approach is easy, safe and demands...
Clinical, MRI findings and arthroscopic correlation of the posterior horn meniscal injuries of the knee joint
The knee joint is one of the most commonly injured joint due to sports activities fall from a bike and fall at home so they come with pain especially in acute condition its very difficult to rely only on the clinical exa...