A Comparative Evaluation of Rapid Card Test with Enzyme- Linked Immunosorbent Assay for the Detection of HBsAg Among Pregnant Women in a Tertiary Care Hospital
Journal Title: International Archives of BioMedical and Clinical Research - Year 2019, Vol 5, Issue 1
Abstract
Background: Hepatitis B virus infection is an important health problem and a leading cause of death worldwide. The most important marker for HBV infection is HBsAg. A proper identification of kit is required for proper diagnosis of infection, as well as disease management and prevention. Aims& Objective: - The aim of the present study was to compare rapid HBsAg detection ICT kits for the screening of HBV infection with gold standard ELISA method. Methods: The study comprised 500 blood samples of pregnant women. These samples were tested with ICT kits of (Hepa Card Company) and ELISA (HEPLISA by J. Mitra.). Results: In present study we found 100% sensitivity, 99.59% specificity, 81.81% positive predictive value ,100%Negative predictive value and 99.60% diagnostic efficiency of rapid card test with comparison to ELISA for HBsAg detection. Conclusion: The present study concluded that the overall performance of the rapid ICT kit for HBsAg was equally sensitive to ELISA and yet they were cheap and quicker. It can be recommended that ELISA comparable rapid devices may be allowed to be used for preliminary screening of HBsAg especially in remote areas or where cost is an issue.
Authors and Affiliations
Megha Sharma, Saroj Golia, S K Mehra, Manoj V Jani
Keywords
Related Articles
- EP ID EP568026
- DOI 10.21276/iabcr.2019.5.1.09
- Views 101
- Downloads 0
Evaluation of Nephroprotective Effect of Ethanolic Extract of Leaves of Aloe barbadensis against Gentamicin Induced Nephrotoxicity in Rats
Background: To evaluate the nephroprotective effect of ethanolic extract of leaves of Aloe barbadensis against gentamicin induced nephrotoxicity in albino rats. Methods: In the present study 24 albino rats of 120-150gm w...
A Prospective Observational Study on Maternal and Fetal Outcome in Eclampsia in a Tertiary Care Hospital
Background: To study maternal outcome in eclampsia in relation to respiratory complications, fever, DIC, renal system affection and electrolyte imbalance. (2) To study the fetal outcome in eclampsia in relation to small...
Impact of Knowledge, Attitude and Practice on Iron Deficiency Anaemia Status Among Females of Reproductive Age Group (20- 21-year-old) Studying in Government Home Economics College Lahore, Pakistan
Background: Iron deficiency anemia has emerged as a major public health issue in developed and developing countries. According to WHO 29% of all women of reproductive age group are diagnosed to have anemia. Objectives:1)...
Abnormal Papanicolaou Test: Results and Risk Factors Among Women of Uttarakhand
Background: Cervical cancer is a significant health issue worldwide. About 493 million new cases of cervical cancer are diagnosed each year. About 274 thousand women die from this disease annually and 83% of these cases...
Social Determinants of Low Back Pain in Females of Reproductive Age Group Residing in Urban Lahore, Pakistan
Background: Nonspecific low back pain (LBP) is a common problem among females of reproductive age group that leads to low quality of life to a greater extent. Nonspecific LBP is other than any diagnosed pathological or s...