A Comparative Study between Intravenous Thiopentone Sodium and Propofol on the Cardiovascular Changes after Electroshock in Patients Undergoing Electroconvulsive Therapy
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 6
Abstract
Introduction: Electroconvulsive therapy is also known as Electroshock or Shock therapy or Electroplexy. Objectives: To study the cardiovascular changes between intravenous Thiopentone Sodium and Propofol groups after electroshock in patients undergoing ECT. Material and methods: This study was carried out on psychiatric patients, after clearance from the ethics committee. Each patient underwent a series of prescribed electroconvulsive therapies. In this study, two treatment groups were included: ECT with Thiopentone Sodium (Group A) and ECT with Propofol (Group B), as induction agents. A total of 60 cases were included in this study. Analysis of the quantitative was done by the Unpaired t - test using the statistical software: SPSS. Result: Increase in then mean heart after induction in both the groups was statistically not significant. After 1 min, the rise in the mean heart rate post electroconvulsive therapy was significant, which then gradually decreased over the study period but never reached the base line. These changes in the mean heart rate were not statistically significant. There was also no significant difference in the systolic blood pressure between two groups, with respect to the baseline values. The increase in systolic blood pressure immediately after induction, i.e., pre-electroconvulsive therapy and after electroconvulsive therapy, was statistically significant in both the groups (p value <0.05). Increase in the systolic blood pressure was more marked in the Thiopentone Sodium group and it remained significant till the end of 45-minutes after induction. Conclusion: Propofol, as induction agent, is better with respect to heart rate and systolic blood pressure.
Authors and Affiliations
Roshan M. Shende, Santosh N. Bodkhe, Sonal Agrawal, Pankaj R. Bhople
Keywords
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