A comparative study between ketamine nebulization and betamethasone gel applied over the endotracheal tube cuff for reduction of post-operative sore throat
Journal Title: Medpulse International Journal of Anesthesiology - Year 2019, Vol 9, Issue 1
Abstract
Background: Endotracheal intubation is necessary in general anesthesia (GA) to control respiration and to protect airway. Larynx and trachea are the most common sites of injury during intubation and usually manifested as local irritation, inflammation, and even necrosis. Aims: This study was undertaken to compare the efficacy of ketamine nebulization and betamethasone gel applied over the endotracheal tube cuff for reduction of postoperative sore throat (POST). Materials and methods: This is a randomized, prospective study of evaluating the efficacy of ketamine nebulisation with betamethasone gel and lignocaine jelly applied over the endotracheal tube cuff for the reduction of postoperative sorethroat (POST). Patients were randomly divided in to ketamine group (group K), betamethasone group (group B) and lignocaine group (group L). In the postoperative period patients were observed at immediately after extubation (0 h), 2, 6, 12 and 24 h for POST which was graded on a four-point scale. Results: The overall incidence of POST in this study was 30%. Out of this POST occurred only in 20% of the patients in ketamine group (K), 23.3% of the patients in betamethasone group (B) compared to 46.6 % in lignocaine group (L) (control).The incidence of POST at 0, 2, 6, 12, 24 hrs was 10%, 10%, 16.6%, 10% and6.6% respectively in ketamine nebulisation group; 10%, 16.6%, 13.3%, 10% and6.6% respectively in betamethasone gel group and 33.3%, 40%, 46.6%, 40%,36.6% in lignocaine jelly group respectively. Conclusion: This study concludes that nebulization with ketamine preoperatively and betamethasone gel applied over endotracheal tube cuff are equally effective in reduction of POST.
Authors and Affiliations
Hegde Uthkala Bhaskar, K Selvaraju, S AnkalaGowri Shankar Devar, Arjun N R, R Ajay Babu
Keywords
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- EP ID EP520912
- DOI 10.26611/10159116
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