A Comparative Study between Ropivacaine with Dexmedetomidine and Ropivacaine with Fentanyl in Lower Abdominal and Lower Limb Surgeries for Postoperative Epidural Analgesia
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2017, Vol 4, Issue 2
Abstract
AIM: Clinical evaluation of efficacy of adding Dexmedetomidine and Fentanyl to Ropivacaine in lower abdominal and lower limb surgeries . Method: This was a randomized double blind study of postoperative epidural analgesia was done in 100 patients divided into 50 patients each, Group-A Patients received 15ml of 0.2% Ropivacaine + 1mcg/kg of Dexmedetomidine and Group-B Patients received 15ml of 0.2% of Ropivacaine + 1mcg/kg of Fentanyl and onset, duration of analgesia, sedation score, visual analogu scale(VAS) were assessed. Results: The onset of analgesia in Group A was 8.21min and in Group B it was 10.23 min, which is statistically significant (P<0.05). Duration of analgesia in Group A was 336 min when compared to Group B which was 260min (p<0.05). No. of Patients with Sedation score of grade 2 and 3 are more in Group-A than in Group-B. There was a significant difference of VAS score between the two groups at 15 minutes, 30mins, 45mins, 60mins, 120 min, 180 min, 240 min and 330mins post operatively (p value < 0.05) that the A group had lower VAS score then B group. Conclusion: Dexmedeto-midine as an adjuvant to Ropivacaine in epidural analgesia seems to be a better alternatiec to Fentanyl, as it provides comparable stable hemodynamics, early onset of analgesia, prolonged post-op analgesia, and much better sedation levels.
Authors and Affiliations
Prabhavathi R.
Keywords
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- EP ID EP466165
- DOI 10.21088/ijaa.2349.8471.42(pt-II)17.5
- Views 93
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