A comparative study between transdermal patches of Buprenorphine andFentanyl for postoperative pain relief following orthopaedic surgery underregional anaesthesia
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Abstract: Transdermal buprenorphine and fentanyl is commonly used for chronic pain management. Our aim was to evaluate the efficacy of transdermal buprenorphine and fentanyl patch in postoperative acute pain management.All patients were randomized into two groups (n=30 in each group) using a computer generated random number table. Group B: Buprenorphine (10mcg/h) patch and Group F: Fentanyl (25mcg/h) patch. Both group received patch 12hr prior to surgery. Haemodynamic and analgesic effects were compared by using analysis of variance (ANOVA) followed by Turkey’s post hoc test. The side effects were compared using the Chi-square test.Hemodynamic changes were not statistically different in both groups. At the end of surgery VAS score of Group A patients was lower as compared to Group B on day 1,2 and 3 but not statistically significant. Sedation was more in group A patients in comparison to group B. The transdermal buprenorphine patch was as effective as fentanyl patch in attenuating postoperative pain and maintaining hemodynamic stability. Keywords:Analgesia, Hemodynamic, Patch, Transdermal delivery system
Authors and Affiliations
Rekha Das, Sumita Mohanty, Sidharth Sraban Routray, Abhilash Dash, Deepak Narayan Sahoo
Keywords
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