A comparative study between transdermal patches of Buprenorphine andFentanyl for postoperative pain relief following orthopaedic surgery underregional anaesthesia
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Abstract: Transdermal buprenorphine and fentanyl is commonly used for chronic pain management. Our aim was to evaluate the efficacy of transdermal buprenorphine and fentanyl patch in postoperative acute pain management.All patients were randomized into two groups (n=30 in each group) using a computer generated random number table. Group B: Buprenorphine (10mcg/h) patch and Group F: Fentanyl (25mcg/h) patch. Both group received patch 12hr prior to surgery. Haemodynamic and analgesic effects were compared by using analysis of variance (ANOVA) followed by Turkey’s post hoc test. The side effects were compared using the Chi-square test.Hemodynamic changes were not statistically different in both groups. At the end of surgery VAS score of Group A patients was lower as compared to Group B on day 1,2 and 3 but not statistically significant. Sedation was more in group A patients in comparison to group B. The transdermal buprenorphine patch was as effective as fentanyl patch in attenuating postoperative pain and maintaining hemodynamic stability. Keywords:Analgesia, Hemodynamic, Patch, Transdermal delivery system
Authors and Affiliations
Rekha Das, Sumita Mohanty, Sidharth Sraban Routray, Abhilash Dash, Deepak Narayan Sahoo
Keywords
Related Articles
- EP ID EP372188
- DOI -
- Views 64
- Downloads 0
Granulomatous mastitis-Can fine needle aspiration cytology avoids unnecessary biopsy?
Abstract: The study aimed to establish the role of FNAC in diagnosing Idiopathic granulomatous mastitis and thus avoid unnecessary biopsy. A retro prospective study of the number of breast aspirations over a period of th...
Role of CT Guided FNAC in Diagnosing Lung Carcinoma and It’s Correlation with the Socio-demographic Profile in a Tertiary Health Care Center in the KumaonRegion of Uttarakhand
Abstract: In remote regions like hills of Uttarakhand, the health care facilities are still in preliminary phase. Most of the cases, even the treatable once, are lost due to lack of awareness and meager diagnostic modali...
Self Medication among Second Year Medical Students in a Teaching Hospital
Abstract: The study was aimed at assessing self medication among second year medical students using a questionnaire. Of total of 200 students, 94(47 %) practiced self medication at least once in the last six months prior...
Co-infection with Cryptosporidium, Isospora and Giardia Lamblia in a Patient Living with HIV and AIDS- a Case Report
A thirty nine year old male positive for Human Immunodeficiency Virus and AIDS, was found to be positive for three different opportunistic parasitic infections. Cryptosporidium, Isospora and Giardia lamblia were simultan...
Pregabalin Intoxication in a Patient with Heroin Addiction
Abstract: Pregabalin is an anticonvulsant which is an analog of gamma-aminobutiric. It increases normal GABA levels by binding to α2-δ subunit in voltage sensitive calcium channels and inhibiting excitator neuro-transmit...